Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 62 clinical trials
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

metastatic prostate cancer
bicalutamide
measurable disease
abiraterone
hormone therapy
Epic Care Cyberknife Center
 (0.9 away) Contact site
  • 1518 views
  • 11 May, 2021
  • +470 other locations
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

This phase II trial studies how well inotuzumab ozogamicin works in treating younger patients with B-lymphoblastic lymphoma or CD22 positive B acute lymphoblastic leukemia that has come back (relapsed) or does not respond to treatment (refractory). Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a toxic agent called …

Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 0 views
  • 30 May, 2021
  • +69 other locations
Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

This phase II trial studies the effect of sacituzumab govitecan in treating patients with HER2-negative breast cancer that has spread to the brain (brain metastases). Sacituzumab govitecan is a monoclonal antibody, called sacituzumab, linked to a chemotherapy drug, called govitecan. Sacituzumab is a form of targeted therapy because it attaches …

Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 0 views
  • 24 May, 2021
  • +169 other locations
A Study of LY3437943 in Participants With Type 2 Diabetes

The main purpose of this study is to evaluate the efficacy and safety of LY3437943 in participants with type 2 diabetes (T2D) who failed to achieve adequate glycemic control on diet and exercise alone or on a stable dose of metformin. This study will last about 43 weeks.

metformin
hemoglobin a1c
Diablo Clinical Research, Inc.
 (2.2 away) Contact site
  • 0 views
  • 20 Jun, 2021
  • +40 other locations
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well olaparib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with defects in deoxyribonucleic acid (DNA) damage repair genes that have spread to other places in the body (advanced) and have come back (relapsed) or do not respond …

myelosuppressive chemotherapy
metastatic disease
platelet transfusion
international normalized ratio
cytotoxic chemotherapy
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 199 views
  • 21 Jun, 2021
  • +73 other locations
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well vemurafenib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with BRAF V600 mutations that have spread to other places in the body (advanced) and have come back (recurrent) or do not respond to treatment (refractory). Vemurafenib may …

myelosuppressive chemotherapy
metastatic disease
platelet transfusion
hematopoietic stem cell transplantation
131i-mibg
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 236 views
  • 20 Jun, 2021
  • +74 other locations
Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well larotrectinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with NTRK fusions that have spread to other places in the body and have come back or do not respond to treatment. Larotrectinib may stop the growth of …

myelosuppressive chemotherapy
metastatic disease
platelet transfusion
brain metastasis
nitrosoureas
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 351 views
  • 20 Jun, 2021
  • +82 other locations
Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well erdafitinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that have spread to other places in the body and have come back or do not respond to treatment with FGFR mutations. Erdafitinib may stop the growth of …

myelosuppressive chemotherapy
metastatic disease
platelet transfusion
pulse oximetry
131i-mibg
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 261 views
  • 22 Jun, 2021
  • +80 other locations
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well samotolisib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with TSC or PI3K/MTOR mutations that have spread to other places in the body (metastatic) and have come back (recurrent) or do not respond to treatment (refractory). Samotolisib …

myelosuppressive chemotherapy
metastatic disease
platelet transfusion
131i-mibg
cytotoxic chemotherapy
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 377 views
  • 20 Jun, 2021
  • +83 other locations
S1613 Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

This randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as trastuzumab …

braf gene
skin cancer
neuropathy
ejection fraction
unstable angina
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 419 views
  • 20 May, 2021
  • +829 other locations