Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 60 clinical trials
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating …

medulloblastoma
MRI
immunohistochemistry
seizure
x-rays
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 119 views
  • 03 Jun, 2021
  • +134 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

brain metastasis
osimertinib
cytology specimen collection procedure
fgfr inhibitor
cutaneous squamous cell carcinoma
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 6087 views
  • 13 Jun, 2021
  • +1015 other locations
Veliparib Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

This phase II trial studies how well veliparib, radiation therapy, and temozolomide work in treating patients with newly diagnosed malignant glioma without H3 K27M or BRAFV600 mutations. Poly adenosine diphosphate (ADP) ribose polymerases (PARPs) are proteins that help repair DNA mutations. PARP inhibitors, such as veliparib, can keep PARP from …

MRI
immunohistochemistry
seizure
anaplastic astrocytoma
x-rays
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 403 views
  • 14 Jun, 2021
  • +110 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

cns disease
pheochromocytoma
corticotropin
other malignancy
systemic therapy
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 5957 views
  • 13 Jun, 2021
  • +812 other locations
Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)

This study will examine the safety and efficacy of pembrolizumab (MK-3475) in combination with chemotherapy in children and young adults with newly diagnosed classical Hodgkin Lymphoma (cHL) who are slow early responders (SERs) to frontline chemotherapy.

lymphoma
vinblastine
prednisone
vincristine
dacarbazine
Kaiser Permanente - Oakland ( Site 0047)
 (9.6 away) Contact site
  • 23 views
  • 16 May, 2021
  • +74 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

progesterone receptor
lumpectomy
mammogram
hcv viral load
progesterone
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 43 views
  • 10 May, 2021
  • +492 other locations
A Study of a New Drug Nirogacestat for Treating Desmoid Tumors That Cannot be Removed by Surgery

This phase II trial studies the side effects and how well nirogacestat works in treating patients with desmoid tumors that has grown after at least one form of treatment by mouth or in the vein that cannot be removed by surgery. Nirogacestat may stop the growth of tumor cells by …

temsirolimus
tamoxifen
sirolimus
cardiac dysrhythmias
imatinib
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 0 views
  • 30 May, 2021
  • +38 other locations
Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

This phase II trial studies the effect of sacituzumab govitecan in treating patients with HER2-negative breast cancer that has spread to the brain (brain metastases). Sacituzumab govitecan is a monoclonal antibody, called sacituzumab, linked to a chemotherapy drug, called govitecan. Sacituzumab is a form of targeted therapy because it attaches …

Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 0 views
  • 24 May, 2021
  • +169 other locations
Selpercatinib for the Treatment of Advanced Solid Tumors Lymphomas or Histiocytic Disorders With Activating RET Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well selpercatinib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphomas, or histiocytic disorders that have activating RET gene alterations. Selpercatinib may block the growth of cancer cells that have specific genetic changes …

cns metastases
cancer treatment
colony stimulating factor
RET
131i-mibg
Kaiser Permanente-Oakland
 (9.2 away) Contact site
  • 17 views
  • 13 Jun, 2021
  • +87 other locations
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis

The purpose of this study is to assess the safety and efficacy of various dose levels of NG101 compared with placebo in adult participants with gastroparesis during 12 weeks of treatment.

abdominal pain
obstruction
nausea
early satiety
vomiting
John Muir Physician Network Clinical Research Center
 (8.8 away) Contact site
  • 72 views
  • 09 Jun, 2021
  • +60 other locations