Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 59 clinical trials
Multiple Dose Study to Evaluate the Efficacy Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus

This is a randomized, placebo-controlled, double-blind study to evaluate the efficacy, safety, and pharmacodynamics (PD) of multiple doses of REMD-477 in subjects who have Type 1 diabetes and are currently receiving insulin treatment. This study will determine whether REMD-477 can decrease daily insulin requirements and improve glycemic control after 12 …

Diablo Clinical Research
 (2.2 away) Contact site
  • 866 views
  • 21 Oct, 2020
  • +10 other locations
Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia

This phase II trial studies how stopping tyrosine kinase inhibitors will affect treatment-free remission in patients with chronic myeloid leukemia in chronic phase. When the level of disease is very low, it's called molecular remission. TKIs are a type of medication that help keep this level low. However, after being …

Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 2 views
  • 20 Aug, 2020
  • +24 other locations
Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery

This pilot phase II trial studies how well pembrolizumab works in treating patients with desmoplastic melanoma (DM) that can be removed by surgery (resectable) or cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere …

Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 91 views
  • 25 Nov, 2020
  • +193 other locations
Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status

This is a phase II trial to examine the efficacy of neratinib plus trastuzumab or neratinib plus cetuximab in patients with "quadruple wild-type" (all RAS/NRAS/BRAF/PIK3CA wild-type), metastatic colorectal cancer based on HER2 status (amplified, non-amplified [wild-type] or mutated). Patients must have confirmed quadruple wild-type (WT) genotype, via NSABP MPR-1 or …

platelet count
metastasis
ct scan
PIK3CA
panitumumab
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 114 views
  • 25 Nov, 2020
  • +47 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to …

covid-19
sore throat
dyspnea
pharyngitis
myalgia
Infect Disease Doctors Med Grp
 (4.7 away) Contact site
  • 2399 views
  • 23 Nov, 2020
  • +157 other locations
A Phase 2 Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

The reason for this study is to see if the study drug LY3209590 is safe and effective in participants with type 2 diabetes.

drug test
body mass index
hemoglobin a1c
metformin
insulin
Diablo Clinical Research
 (4.7 away) Contact site
  • 352 views
  • 25 Nov, 2020
  • +125 other locations
Pomalidomide in Combination With Low-dose Dexamethasone or Pomalidomide in Combination With Low-dose Dexamethasone and Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Following Lenalidomide-based Therapy in the First or Second Line Setting

This trial will evaluate the efficacy and safety of combination of pomalidomide (POM) and low-dose dexamethasone (LD-Dex) (Cohort A) or the combination of pomalidomide (POM) , daratumumab (DARA) and low-dose dexamethasone (LD-Dex) (Cohort B) in subjects with relapsed or refractory multiple myeloma who have received a first or second line …

vasectomy
measurable disease
pomalidomide
bone marrow procedure
lenalidomide
Bay Area Cancer Research Group, LLC
 (3.1 away) Contact site
  • 79 views
  • 16 Apr, 2020
  • +47 other locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating …

platelet count
mri of spine
brain tumor
residual tumor
cancer
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 119 views
  • 25 Nov, 2020
  • +127 other locations
Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

This National Cancer Institute (NCI)-NRG ALK Protocol phase II trial studies how well a combination of different biomarker/ALK inhibitors work in treating patients with stage IV ALK positive non-squamous non-small cell lung cancer. Lorlatinib, ceritinib, alectinib, brigatinib, ensartinib, and crizotinib may stop the growth of tumor cells by blocking some …

metastasis
progressive disease
kinase inhibitor
oophorectomy
brigatinib
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 143 views
  • 25 Nov, 2020
  • +383 other locations
Veliparib Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

This phase II trial studies how well veliparib, radiation therapy, and temozolomide work in treating patients with newly diagnosed malignant glioma without H3 K27M or BRAFV600 mutations. Poly adenosine diphosphate (ADP) ribose polymerases (PARPs) are proteins that help repair DNA mutations. PARP inhibitors, such as veliparib, can keep PARP from …

cancer
glioblastoma multiforme
MRI
anaplastic astrocytoma
malignant glioma
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 403 views
  • 25 Nov, 2020
  • +103 other locations