Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 11 clinical trials
A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

This is a Phase 2/3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult and adolescent patients with active eosinophilic esophagitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to receive 6 doses of …

ak002
dysphagia
hysterectomy
eosinophil count
eosinophilia
Allakos Investigational Site
 (4.7 away) Contact site
  • 115 views
  • 26 Feb, 2021
  • +60 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 193 views
  • 27 Jan, 2021
  • +843 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Epic Care Cyberknife Center
 (0.9 away) Contact site
  • 135 views
  • 28 Feb, 2021
  • +506 other locations
Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

There are two study questions we are asking in this randomized phase II/III trial based on a blood biomarker, Epstein Barr virus (EBV) deoxyribonucleic acid (DNA) for locoregionally advanced non-metastatic nasopharyngeal cancer. All patients will first undergo standard concurrent chemotherapy and radiation therapy. When this standard treatment is completed, if …

Kaiser Permanente Oakland-Broadway
 (9.6 away) Contact site
  • 292 views
  • 26 Jan, 2021
  • +134 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to …

covid-19
dyspnea
fever
myalgia
sore throat
Infect Disease Doctors Med Grp
 (4.7 away) Contact site
  • 2399 views
  • 24 Feb, 2021
  • +169 other locations
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

cancer therapy
carcinoma
glomerular filtration rate
vincristine
carboplatin
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 178 views
  • 14 Feb, 2021
  • +133 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

measurable disease
gm-csf
metastasis
nitrosoureas
platelet count
Kaiser Permanente-Walnut Creek
 (2.8 away) Contact site
  • 46 views
  • 28 Feb, 2021
  • +399 other locations
An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)

This is an open-label, multicenter, dose confirmation, and PK study of JZP-458 in patients (of any age) with ALL/LBL who are hypersensitive to E. coli-derived asparaginases (allergic reaction or silent inactivation). This study is designed to assess the tolerability and efficacy of JZP-458 (only in patients who develop hypersensitivity to …

lymphoma
lymphoblastic lymphoma
asparaginase
lymphoid leukemia
Kaiser Permanente - Oakland Medical Center
 (9.6 away) Contact site
  • 5 views
  • 28 Jan, 2021
  • +63 other locations
Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Treating Patients With Limited Stage or Extensive Stage Small Cell Lung Cancer

This randomized phase II/III trial studies how well whole-brain radiation therapy works and compares it with or without hippocampal avoidance in treating patients with small cell lung cancer that is found in one lung, the tissues between the lungs, and nearby lymph nodes only (limited stage) or has spread outside …

x-rays
cns metastases
cancer
metastasis
serum pregnancy test
Kaiser Permanente Oakland-Broadway
 (9.6 away) Contact site
  • 525 views
  • 27 Jan, 2021
  • +169 other locations
Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and …

Epic Care Cyberknife Center
 (0.9 away) Contact site
  • 0 views
  • 18 Feb, 2021
  • +529 other locations