Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 12 clinical trials
A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

This is a Phase 2/3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult and adolescent patients with active eosinophilic esophagitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to receive 6 doses of …

eosinophil count
hysterectomy
eosinophilia
ak002
dysphagia
Allakos Investigational Site
 (4.7 away) Contact site
  • 115 views
  • 22 May, 2021
  • +68 other locations
Study to Describe the Safety Tolerability Immunogenicity and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals

This is a Phase 1/2/3, randomized, placebo-controlled, observer-blind, dose-finding, vaccine candidate-selection, and efficacy study in healthy individuals. The study consists of 2 parts: Phase 1: to identify preferred vaccine candidate(s) and dose level(s); Phase 2/3: an expanded cohort and efficacy part. The study will evaluate the safety, tolerability, and immunogenicity …

covid-19
SARS
Diablo Clinical Research, Inc.
 (4.7 away) Contact site
  • 24080 views
  • 07 Jun, 2021
  • +196 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19. Samples will be taken from the back of the nose to determine how much virus is in …

covid-19
fever
cough
pharyngitis
sore throat
Infect Disease Doctors Med Grp
 (4.7 away) Contact site
  • 2399 views
  • 13 Jun, 2021
  • +205 other locations
Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

There are two study questions we are asking in this randomized phase II/III trial based on a blood biomarker, Epstein Barr virus (EBV) deoxyribonucleic acid (DNA) for locoregionally advanced non-metastatic nasopharyngeal cancer. All patients will first undergo standard concurrent chemotherapy and radiation therapy. When this standard treatment is completed, if …

Kaiser Permanente Oakland-Broadway
 (9.6 away) Contact site
  • 292 views
  • 07 Jun, 2021
  • +135 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

white blood cell count
monoclonal antibodies
cancer
nitrosoureas
liver metastasis
Kaiser Permanente-Walnut Creek
 (2.8 away) Contact site
  • 46 views
  • 13 Jun, 2021
  • +429 other locations
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

carcinoma
etoposide
liver cancer
cancer
fluorouracil
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 178 views
  • 13 Jun, 2021
  • +136 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Epic Care Cyberknife Center
 (0.9 away) Contact site
  • 135 views
  • 13 Jun, 2021
  • +537 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations
Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and …

Epic Care Cyberknife Center
 (0.9 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +546 other locations
Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Treating Patients With Limited Stage or Extensive Stage Small Cell Lung Cancer

This randomized phase II/III trial studies how well whole-brain radiation therapy works and compares it with or without hippocampal avoidance in treating patients with small cell lung cancer that is found in one lung, the tissues between the lungs, and nearby lymph nodes only (limited stage) or has spread outside …

serum pregnancy test
cns metastases
metastasis
cancer
x-rays
Kaiser Permanente Oakland-Broadway
 (9.6 away) Contact site
  • 525 views
  • 07 Jun, 2021
  • +181 other locations