Sherman Oaks, California Clinical Trials
A listing of Sherman Oaks, California clinical trials actively recruiting patient volunteers.
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)
This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …
- 213 views
- 28 Jul, 2021
- +188 other locations
VIVID-1, a clinical research study for adults 18–80 with moderately to severely active Crohn’s disease.
A phase 3 research study of an injectable investigational medicine for adults ages 18 to 80 with moderate to severe Crohn’s disease. Note that study participants may receive the investigational medication, a currently approved Crohn’s medication, or placebo. The study comprises four periods: screening, treatment period 1, treatment period 2, …
- 66 views
- 02 Aug, 2021
- +75 other locations
We are currently recruiting patients with Generalized Pustular Psoriasis (GPP). This study investigates the Efficacy and safety of ANB019.
The study drug consists of an intravenous (IV) investigational treatment, that will be administered on Day 1, followed by 3 subcutaneous doses of the study treatment on Days 29, Day 57 and Day 85. Several blood samples will be collected throughout the study. Your participation in the biopsy portion of …
- 28 views
- 22 Dec, 2020
- +7 other locations
We are currently recruiting patients with Palmoplantar Pustulosis (PPP). This study investigates the Efficacy and safety of ANB019.
The study drug consists of a sub-cutaneous investigational treatment or a placebo, that will be administered on Day 1, followed by 3 doses of the study treatment on Days 29, Day 57 and Day 85. Several blood samples will be collected throughout the study. Your participation in the biopsy portion …
- 28 views
- 22 Dec, 2020
- +23 other locations
Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation
The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of itacitinib in participants with post-lung transplant bronchiolitis obliterans syndrome (BOS).
- 11 views
- 23 Nov, 2020
- +6 other locations
A Phase 1/2 Trial of MRTX849 in Combination with TNO155 in Patients with Advanced Solid Tumors with KRAS G12C Mutation
Characterize the safety and tolerability, and evaluate Pharmacokinetics of MRTX849 in combination with TNO155 in patients with advanced solid tumor malignancies with KRAS G12C mutation. MRTX849 is an orally available small molecute inhibitor of KRASG12C. TNO155 is a selective, orally bioavailable allosteric inhibitor of wild type SHP2.
- 114 views
- 19 Feb, 2021
- +9 other locations
We are currently recruiting participants for the BLUEPRINT study. This study investigates the effectiveness, safety, and tolerability of the drug BLU-5937 for chronic itch in people with eczema.
The BLUEPRINT study consists of taking two tablets orally, twice a day, for a period of 4 weeks. This treatment is experimental. You will have 50% chance to receive BLU-5937 and 50% chance to receive the placebo. There will be a total of 5 visits at the clinic and 2 …
- 0 views
- 10 Dec, 2020
- +24 other locations
[ONLINE] Alzheimer’s ‘The Family Disease’: Examining the Effects of Resilience on Preparedness and Compassion in Asian Family Caregivers
This study is looking for people of Asian ethnicity who care for a family member who has Alzheimer’s. This is an online survey study. Contact Person Khushbu Sheth 530-715-0086 firstname.lastname@example.org
- 40 views
- 01 Oct, 2020
- +250 other locations
This study is looking for families who have one or more individuals with early-onset Alzheimer’s. The study is interested in the genetic factors across family members. This may help to develop methods for predicting or diagnosing early-onset Alzheimer’s.
- 2 views
- 26 May, 2021
- +242 other locations
This study is looking for people aged 60-90 who have mild cognitive impairment. The study is also looking for people with normal cognition, as a comparison. The study is testing a medical device to determine whether brain stimulation improves memory.
- 15 views
- 15 Sep, 2020
- 1 location