Sherman Oaks, California Clinical Trials

A listing of Sherman Oaks, California clinical trials actively recruiting patient volunteers.

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Found 1518 clinical trials
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A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

platinum-based chemotherapy
lung carcinoma
lung cancer
advanced lung cancer
advanced non-squamous non-small cell lung cancer
University of California Los Angeles - Jonsson Comprehensive Cancer Center
 (5.9 away) Contact site
  • 213 views
  • 28 Jul, 2021
  • +188 other locations
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VIVID-1, a clinical research study for adults 18–80 with moderately to severely active Crohn’s disease.

A phase 3 research study of an injectable investigational medicine for adults ages 18 to 80 with moderate to severe Crohn’s disease. Note that study participants may receive the investigational medication, a currently approved Crohn’s medication, or placebo. The study comprises four periods: screening, treatment period 1, treatment period 2, …

gastrointestinal disorder
crohn's disease
inflammatory bowel disease
gastrointestinal diseases
VIVID-1 Study Center
 (6.7 away) Contact site
  • 66 views
  • 02 Aug, 2021
  • +75 other locations
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We are currently recruiting patients with Generalized Pustular Psoriasis (GPP). This study investigates the Efficacy and safety of ANB019.

The study drug consists of an intravenous (IV) investigational treatment, that will be administered on Day 1, followed by 3 subcutaneous doses of the study treatment on Days 29, Day 57 and Day 85. Several blood samples will be collected throughout the study. Your participation in the biopsy portion of …

psoriasis
skin disease
pustular psoriasis
skin disorder
T. Joseph Raoof, MD, Inc
 (2.1 away) Contact site
  • 28 views
  • 22 Dec, 2020
  • +7 other locations
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We are currently recruiting patients with Palmoplantar Pustulosis (PPP). This study investigates the Efficacy and safety of ANB019.

The study drug consists of a sub-cutaneous investigational treatment or a placebo, that will be administered on Day 1, followed by 3 doses of the study treatment on Days 29, Day 57 and Day 85. Several blood samples will be collected throughout the study. Your participation in the biopsy portion …

psoriasis
skin disease
skin disorder
T. Joseph Raoof, MD, Inc
 (2.1 away) Contact site
  • 28 views
  • 22 Dec, 2020
  • +23 other locations
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Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation

The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of itacitinib in participants with post-lung transplant bronchiolitis obliterans syndrome (BOS).  

bronchiolitis obliterans
organ transplantation
bronchiolitis
lung transplant
University of California, Los Angeles-David Geffen School of Medicine
 (5.4 away) Contact site
  • 11 views
  • 23 Nov, 2020
  • +6 other locations
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A Phase 1/2 Trial of MRTX849 in Combination with TNO155 in Patients with Advanced Solid Tumors with KRAS G12C Mutation

Characterize the safety and tolerability, and evaluate Pharmacokinetics of MRTX849 in combination with TNO155 in patients with advanced solid tumor malignancies with KRAS G12C mutation. MRTX849 is an orally available small molecute inhibitor of KRASG12C. TNO155 is a selective, orally bioavailable allosteric inhibitor of wild type SHP2.

malignant solid tumor
solid tumors
advanced solid tumor
solid tumor
University of California Los Angeles
 (8.5 away) Contact site
  • 114 views
  • 19 Feb, 2021
  • +9 other locations
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We are currently recruiting participants for the BLUEPRINT study. This study investigates the effectiveness, safety, and tolerability of the drug BLU-5937 for chronic itch in people with eczema.

The BLUEPRINT study consists of taking two tablets orally, twice a day, for a period of 4 weeks. This treatment is experimental. You will have 50% chance to receive BLU-5937 and 50% chance to receive the placebo. There will be a total of 5 visits at the clinic and 2 …

dermatitis
atopic dermatitis
atopic dermatitis/eczema
eczema
adult atopic dermatitis
Zenith Research Inc.
 (6.6 away) Contact site
  • 0 views
  • 10 Dec, 2020
  • +24 other locations
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[ONLINE] Alzheimer’s ‘The Family Disease’: Examining the Effects of Resilience on Preparedness and Compassion in Asian Family Caregivers

This study is looking for people of Asian ethnicity who care for a family member who has Alzheimer’s. This is an online survey study. Contact Person Khushbu Sheth 530-715-0086 ksheth@alliant.edu

Online238
 (6.4 away) Contact site
  • 40 views
  • 01 Oct, 2020
  • +250 other locations
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[Remote] Early Onset Alzheimer's Disease study

This study is looking for families who have one or more individuals with early-onset Alzheimer’s. The study is interested in the genetic factors across family members. This may help to develop methods for predicting or diagnosing early-onset Alzheimer’s.

dementia
cognitive impairment
mild cognitive impairment
[Remote] Early Onset Alzheimer's Disease study
 (6.4 away) Contact site
  • 2 views
  • 26 May, 2021
  • +242 other locations
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Memory Research Study

This study is looking for people aged 60-90 who have mild cognitive impairment. The study is also looking for people with normal cognition, as a comparison. The study is testing a medical device to determine whether brain stimulation improves memory.

Jane & Terry Semel Institute for Neuroscience and Human Behavior
 (5.4 away) Contact site
  • 15 views
  • 15 Sep, 2020
  • 1 location