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Pasadena, California Clinical Trials

A listing of Pasadena, California clinical trials actively recruiting patient volunteers.

RESULTS

Found (946) clinical trials

Expanding MRI Access for Patients With New and Existing ICDs and CRT-Ds ( ENABLE MRI)

The objective of this study is to collect data to confirm the safety and effectiveness of the ImageReady™ MR Conditional Defibrillation System when used in the 1.5T MRI environment under the labeled Conditions of Use (Phase I). Additionally, the study will assess medically necessary MR scans according to the labeled ...

Phase N/A

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A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Phase

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Brain Implant for Neural Control of a Computer

The investigators objective is to run human clinical trials in which brain activity recorded through a "brain-chip" implanted in the human brain can be used to provide novel communication capabilities to severely paralyzed individuals by allowing direct brain-control of a computer interface. A prospective, longitudinal, single-arm early feasibility study will ...

Phase N/A

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Providing Closed Loop Cortical Control of Extracorporeal Devices to Patients With Quadriplegia

This research study is being conducted to develop a brain controlled medical device, called a brain-machine interface. The device will provide people with a spinal cord injury some ability to control an external device such as a computer cursor or robotic limb by using their thoughts along with sensory feedback. ...

Phase N/A

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Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial

The PORTICO IDE trial will include approximately 758 randomized subjects at up to 70 investigational sites. The study is powered to analyze the high risk cohort and extreme risk cohort together against a commercially available control for the primary safety and effectiveness endpoints. In addition, data for each cohort will ...

Phase N/A

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Anticoagulation Length of ThErapy and Risk of New Adverse evenTs In Venous thromboEmbolism Study

Venous thromboembolism (VTE) is a leading cause of cardiovascular death and continues to be a major public health issue in the United States. The cornerstone of current VTE treatment is anticoagulation, typically given for 3 months during the acute phase of thrombosis. Afterwards, extended-duration anticoagulation can be considered for selected ...

Phase N/A

0.32 miles

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Safety Follow-up Study in Subjects With Silicone Gel-filled Breast Implants as Compared Both to Saline-filled Breast Implants and to National Norms

Ten year safety study examining rates of rare adverse events, child bearing issues, effects of mammography, MRI compliance and results, and long-term benefit of silicone-filled breast implants.

Phase N/A

0.32 miles

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Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination

This multicenter screening study will be conducted in order to determine a subject's tumor antigen expression profile and HLA subtype, and subsequent eligibility for Adaptimmune sponsored clinical treatment trials studying the safety and efficacy of autologous genetically modified T-cells engineered with enhanced TCRs targeting specific antigens. No treatment intervention will ...

Phase N/A

0.32 miles

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Profiling Biospecimens From Cancer Patients to Screen for Molecular Alterations Related to Treatment Selection

The Strata Trial is a precision oncology collaboration structured as an observational master screening protocol with the aim to match patients to genomically-guided therapeutic protocols and/or approved therapies. Subjects enrolled on the Strata trial will submit surplus, clinical formalin fixed paraffin-embedded (FFPE) tumor specimens for molecular profiling and a test ...

Phase N/A

0.32 miles

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An Adaptive Phase II/III Two-Part Double-Blind Randomized Placebo-controlled Dose-Finding Multi-center Study of the Safety and Efficacy of NaBen as an Add-on Therapy With Clozapine for Residual Symptoms of Refractory Schizophrenia in Adults

This is a Phase II/III, double-blind, randomized, placebo-controlled, two-part, dose-finding, Multi-center study, in which subjects with refractory schizophrenia will be enrolled. This study will be conducted in two parts: In Part 1 (i.e. dose finding portion) of the study One hundred seventy one (171) subjects will be randomized in a ...

Phase

0.32 miles

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