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Los Alamitos, California Clinical Trials

A listing of Los Alamitos, California clinical trials actively recruiting patient volunteers.

RESULTS

Found (11) clinical trials

Over 8 million adults are believed to have Attention Deficit Disorder (ADD) or Attention Deficit Hyperactivity Disorder (ADHD). Adults with ADHD typically have a long history of inattention and a lack of focus. They often experience difficulty managing relationships, raising kids and handling finances. Finding the most effective ADHD treatment ...

Phase N/A

0.66 miles

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Anxiety is a normal part of life—it can even be useful at times. But for some people, anxiety is a persistent problem that interferes with daily activities such as work, school or sleep. This type of anxiety can disrupt relationships, enjoyment of life and, over time, it can lead to ...

Phase N/A

0.66 miles

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2a Study to Assess the Efficacy and Safety of REGN3500 Monotherapy and Combination of REGN3500 Plus Dupilumab in Adult Patients With Moderate-to-Severe Atopic Dermatitis

The primary objective of the study is to evaluate the efficacy of REGN3500 monotherapy compared with placebo treatment in adult patients with moderate-to-severe Atopic dermatitis (AD). Secondary Objectives are to: Evaluate the efficacy of REGN3500 in combination with dupilumab compared with placebo treatment in adult patients with moderate-to-severe AD Assess ...

Phase

2.64 miles

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Systemic Corticosteroids Avoidance Study in Severe Asthma Patients

The overall purpose of this study is to determine the efficacy of fevipiprant (dose 1 and dose 2 once daily), compared with placebo, as add-on to standard-of-care asthma therapy, in terms of avoidance of coricosteroid use over 52 weeks.

Phase

5.34 miles

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Study to Evaluate the Efficacy Safety and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)

This study is being conducted to evaluate in participants with diarrhea-predominant Irritable Bowel Syndrome (IBS-D) the abdominal pain response to BOS-589 after 4 weeks of treatment and to evaluate the overall safety and tolerability of BOS-589 in the treatment of IBS-D during 4 weeks of treatment, relative to placebo (PBO).

Phase

5.69 miles

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Scopolamine in Healthy Volunteers

The investigational product is a combination product comprised of: (a) a vial prefilled with DPI-386 Nasal Gel, and (b) a nasal gel pump attached to the vial during the manufacturing process. For Cohorts 1 through 4, 9 through 10,13, and 14 each 0.12 gram of the gel contains 0.2 mg ...

Phase

6.64 miles

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A Phase 3, randomized (2:2:1), double-blind, 8-week vehicle control efficacy and safety study of ruxolitinib followed by a randomized, double-blind, 44-week long term safety (LTS) extension period.  In the LTS period,  participants initially randomized to vehicle will receive either ruxolitinib 0.75% or 1.5% cream.  All participants will have follow-up assessments ...

Phase

6.91 miles

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Evaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase 2 study in subjects with moderate to severe Hidradenitis Suppurativa. The study is multicenter and will consist of three subject groups. Subjects will be randomized 1:1:1 to a treatment of 10mg avacopan twice daily, 30 mg avacopan twice daily or placebo twice daily ...

Phase

6.91 miles

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A Study to Assess the Efficacy Safety and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis

This is a Phase 2a/b randomized, double-blind, placebo-controlled study to investigate the efficacy, safety, tolerability, PK and immunogenicity of KPL-716 administered subcutaneously (SC) in subjects with prurigo nodularis experiencing pruritus. The Phase 2a portion of the study will enroll up to 100 subjects and will include 2 arms: one active ...

Phase

9.49 miles

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Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) at the End of Shelf Life in Healthy Adults

The vaccine being tested in this study is Takeda's Tetravalent Dengue Vaccine Candidate (TDV). The primary objective of this study is to evaluate the immune response and safety of a naturally aged (>12 months stored at 2C to 8C) lot of TDV in a healthy adult population in country(ies) non-endemic ...

Phase

9.64 miles

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