Hollywood, California Clinical Trials

A listing of Hollywood, California clinical trials actively recruiting patient volunteers.

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Found 26 clinical trials
PRISM Study-Pruritus Relief Through Itch Scratch Modulation

To investigate the anti-pruritic efficacy and safety of Nalbuphine ER (NAL ER) tablets in Prurigo Nodularis. Subjects will be randomized to NAL ER (or matching placebo) with the primary endpoint evaluation at Week 14. During the open label extension, subjects who received NAL ER will continue on NAL ER and …

nalbuphine
Study Site 141
 (7.4 away) Contact site
  • 661 views
  • 12 Jun, 2021
  • +85 other locations
Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia

The main purpose of this study is to evaluate the efficacy and safety of M281 in participants with warm autoimmune hemolytic anemia (wAIHA).

Momenta Investigational Site
 (7.5 away) Contact site
  • 15 views
  • 19 Jun, 2021
  • +138 other locations
Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adult Participants With COVID-19 (MK-4482-002)

This study aims to evaluate the safety, tolerability and efficacy of molnupiravir (MK-4482) compared to placebo. The primary hypothesis is that molnupiravir is superior to placebo as assessed by the percentage of participants who are hospitalized and/or die through Day 29

Ruane Clinical Research Group, Inc. ( Site 2406)
 (2.2 away) Contact site
  • 0 views
  • 19 Jun, 2021
  • +111 other locations
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple therapies in newly diagnosed (ND) and recurrent GBM.

lomustine
recurrent disease
recurrent glioblastoma
gliosarcoma
temozolomide
Cedars Sinai - Samuel Oschin Comprehensive Cancer Institute
 (2.8 away) Contact site
  • 105 views
  • 16 Jun, 2021
  • +35 other locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
Cedars-Sinai Medical Center - West Hollywood /ID# 163851
 (2.8 away) Contact site
  • 604 views
  • 16 Jun, 2021
  • +772 other locations
Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)

The purpose of this study is to compare the efficacy of olaparib (MK-7339) plus pembrolizumab (MK-3475) with chemotherapy plus pembrolizumab after induction with first-line chemotherapy plus pembrolizumab in triple negative breast cancer (TNBC). The primary hypotheses are: Olaparib plus pembrolizumab prolongs progression-free survival (PFS) compared with chemotherapy plus pembrolizumab. Olaparib …

mk-3475
cancer
breast cancer
triple negative breast cancer
taxane
John Wayne Cancer Institute ( Site 0111)
 (9.4 away) Contact site
  • 241 views
  • 10 Jun, 2021
  • +131 other locations
HEALEY ALS Platform Trial - Master Protocol

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.

treatment regimen
edaravone
weakness
riluzole
Cedars-Sinai Medical Center
 (2.8 away) Contact site
  • 144 views
  • 12 Jun, 2021
  • +50 other locations
Study to Evaluate the Safety Tolerability Pharmacokinetics and Efficacy of Remdesivir (GS-5734 ) in Participants From Birth to < 18 Years of Age With Coronavirus Disease 2019 (COVID-19)

The primary objectives of this study are to evaluate the safety, tolerability, and pharmacokinetics (PK) of remdesivir (RDV) in participants with laboratory-confirmed coronavirus disease 2019 (COVID-19) aged 0 days to < 18 years.

coronavirus infection
SARS
remdesivir
covid-19
Children's Hospital Los Angeles
 (2.2 away) Contact site
  • 134 views
  • 14 Jun, 2021
  • +38 other locations
Study to Describe the Safety Tolerability Immunogenicity and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals

This is a Phase 1/2/3, randomized, placebo-controlled, observer-blind, dose-finding, vaccine candidate-selection, and efficacy study in healthy individuals. The study consists of 2 parts: Phase 1: to identify preferred vaccine candidate(s) and dose level(s); Phase 2/3: an expanded cohort and efficacy part. The study will evaluate the safety, tolerability, and immunogenicity …

covid-19
SARS
Kaiser Permanente Los Angeles Medical Center
 (2.8 away) Contact site
  • 24080 views
  • 07 Jun, 2021
  • +196 other locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

This phase II/III trial studies how well a reduced dose of radiation therapy works with nivolumab compared to cisplatin in treating patients with human papillomavirus (HPV)-positive oropharyngeal cancer that is early in its growth and may not have spread to other parts of the body (early-stage), and is not associated …

cancer
chemotherapy regimen
cavities
measurable disease
head and neck cancer
City of Hope South Pasadena
 (10.0 away) Contact site
  • 16 views
  • 19 Jun, 2021
  • +224 other locations