North Little Rock, Arkansas Clinical Trials

A listing of North Little Rock, Arkansas clinical trials actively recruiting patient volunteers.

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Found 6 clinical trials
A Study to Assess ASP0598 Otic Solution Following Topical Application in the Ear in Subjects With Chronic Tympanic Membrane Perforation (CTMP)

The primary purpose of this study is to evaluate the safety and tolerability of ASP0598 Otic Solution. This study will also evaluate the efficacy of ASP0598 otic solution.

University of Arkansas
 (2.3 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +17 other locations
Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201) a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered Non-infectious Virus (AAV) as a "Shuttle".

In this study researchers want to gather more information about safety and effectiveness of BAY 2599023 (DTX201), a drug therapy that delivers the human factor VIII gene into the human body by use of a viral vector to treat the disease. By replacing the defective gene with a healthy copy …

antihemophilic factor
severe haemophilia a
coagulation factor
bleeding tendency
Arkansas Children's Hospital
 (2.9 away) Contact site
  • 203 views
  • 02 Aug, 2021
  • +34 other locations
A Study of Ponatinib With Chemotherapy in Children Teenagers and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

This study is about an anticancer drug called ponatinib which is a tyrasine kinase inhibitor given with chemotherapy to children, teenagers, and young adults up to 21 years of age with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia who have relapsed or are resistant to other treatment. The main aims of this …

Arkansas Children's Hospital
 (2.3 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +59 other locations
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia"

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orally once daily in pediatric patients with newly diagnosed chronic phase Ph+ CML (ND CML) and pediatric patients with Ph+CML who have received at least one prior TKI therapy (R/I CML), …

graft versus host disease
biologic agent
myeloid leukemia
chronic myeloid leukemia
major surgery
Arkansas Children's Hospital
 (2.9 away) Contact site
  • 0 views
  • 29 Jul, 2021
  • +31 other locations
Vaccination of Triple Negative Breast Cancer Patients

The purpose of this study is to evaluate a new investigational cancer vaccine, P10s-PADRE in combination with standard neoadjuvant chemotherapy and surgery in patients with clinical stage I, II or III triple negative breast cancer (TNBC). This study will compare the vaccine plus standard neoadjuvant chemotherapy and surgery to standard …

paclitaxel
cyclophosphamide
mammogram
breast cancer
HER2
University of Arkansas for Medical Sciences
 (4.6 away) Contact site
  • 17 views
  • 01 Aug, 2021
  • +1 other locations
First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene Mutations

VT30-101 is a 2-part first-in-human trial of topically administered VT30 to subjects with cutaneous venous malformations, lymphatic malformations, or mixed venolymphatic malformations associated with PIK3CA or TEK mutations. Part 1 is a 4-week treatment, open-label, 4-sequence, escalating repeat-application cohort study, with intra-subject and inter-cohort dose escalation. Part 2 is a …

Arkansas Children's Hospital/UAMS
 (2.9 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +14 other locations