North Little Rock, Arkansas Clinical Trials

A listing of North Little Rock, Arkansas clinical trials actively recruiting patient volunteers.

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Found 145 clinical trials
Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

This phase III trial studies how well axillary reverse mapping works in preventing lymphedema in patients with breast cancer undergoing axillary lymph node dissection. Axillary reverse mapping may help to preserve the lymph node drainage system around the breast so as to prevent lymphedema after surgery.

breast surgery
mastectomy
sentinel lymph node biopsy
isosulfan blue
ductal carcinoma in situ
University of Arkansas for Medical Sciences
 (5.1 away) Contact site
  • 25 views
  • 21 Jun, 2021
  • +72 other locations
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and …

primary prevention
cognitive impairment
mild cognitive impairment
hmg-coa reductase inhibitor
atorvastatin
Little Rock VA Medical Center
 (0.9 away) Contact site
  • 104 views
  • 21 Jun, 2021
  • +86 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19. Samples will be taken from the back of the nose to determine how much virus is in …

fever
headache
covid-19
myalgia
cough
Arkansas Clinical Research
 (4.6 away) Contact site
  • 2399 views
  • 23 Jun, 2021
  • +206 other locations
Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

This seamless, adaptive, two-stage, Phase 2b/3, randomized, double-blind, multicenter, parallel-groups, placebo-controlled study will assess the efficacy, safety, and tolerability of belapectin compared with placebo in patients with nonalcoholic steatohepatitis (NASH) cirrhosis and clinical signs of portal hypertension but without esophageal varices at baseline.

pioglitazone
high-density lipoprotein
body mass index
hemoglobin a1c
vitamins
Liver Wellness Center - Little Rock
 (5.1 away) Contact site
  • 0 views
  • 23 Jun, 2021
  • +95 other locations
Pivotal Study to Assess the Efficacy Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate or severe COPD exacerbation (AECOPD) Secondary Objectives: To evaluate the effect of dupilumab administered every 2 weeks on Pre-bronchodilator …

forced expiratory volume
corticosteroids
muscarinic antagonists
bronchodilator
eosinophil count
Investigational Site Number 8400022
 (8.1 away) Contact site
  • 156 views
  • 13 Jun, 2021
  • +202 other locations
Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

Study D9181C00001 is a Phase II, randomised, double-blind, placebo-controlled, parallel group, proof of concept study to evaluate the efficacy, safety, pharmacokinetics (PK) and immunogenicity of MEDI3506 in adult participants with uncontrolled moderate to severe asthma on standard of care (SOC). Up to approximately 80 sites globally will participate in this …

Research Site
 (5.1 away) Contact site
  • 218 views
  • 23 Jun, 2021
  • +71 other locations
A Study to Test if TEV-48574 is Effective in Relieving Asthma

The primary objective of the study is to evaluate the effect of TEV-48574 compared with placebo on loss of asthma control (LoAC) in adult patients with T2-low and non-T2 severe asthma uncontrolled on inhaled corticosteroids plus long-acting beta-agonists (ICS+LABA). The secondary efficacy objective is to evaluate the effect of TEV-48574 …

Teva Investigational Site 14915
 (5.1 away) Contact site
  • 52 views
  • 16 Jun, 2021
  • +69 other locations
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency. The intention of the study is to demonstrate that in participants with mHSPC, the …

Research Site
 (4.6 away) Contact site
  • 109 views
  • 13 Jun, 2021
  • +263 other locations
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Patients 6 to 17 Years of Age

The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of chronic migraine (CM). Secondary objectives are to further demonstrate the efficacy of Fremanezumab as compared to placebo for the preventive treatment of CM, to evaluate the safety and …

fremanezumab
daily headaches
headache
recurrent headaches
chronic migraine
Teva Investigational Site 14281
 (2.9 away) Contact site
  • 0 views
  • 19 Jun, 2021
  • +58 other locations
A Study to Test if Fremanezumab is Effective in Preventing Episodic Migraine in Patients 6 to 17 Years of Age

The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of episodic migraine (EM). Secondary objectives are to further demonstrate the efficacy of Fremanezumab as compared to placebo for the preventive treatment of EM, to evaluate the safety and …

fremanezumab
daily headaches
episodic migraine
headache
recurrent headaches
Teva Investigational Site 14281
 (2.9 away) Contact site
  • 47 views
  • 22 Jun, 2021
  • +58 other locations