North Little Rock, Arkansas Clinical Trials

A listing of North Little Rock, Arkansas clinical trials actively recruiting patient volunteers.

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Found 128 clinical trials
A Pharmacokinetic Study of Tedizolid Phosphate in Pediatric Participants With Gram-Positive Infections (MK-1986-014)

The primary objectives of this study are to describe the single-dose, and multiple dose pharmacokinetics (PK) of intravenous (IV) tedizolid phosphate, or a single dose oral suspension of tedizolid phosphate, when administered to pediatric participants, full-term neonates, and preterm neonates.

Arkansas Children's Hospital ( Site 1012)
 (2.3 away) Contact site
  • 39 views
  • 17 Jun, 2021
  • +28 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

ipilimumab
nitrosoureas
liver metastasis
platelet count
tumor cells
John L McClellan Memorial Veterans Hospital
 (5.1 away) Contact site
  • 46 views
  • 16 Jun, 2021
  • +429 other locations
This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia

This is a study in adults with schizophrenia. The study tests whether a medicine called BI 425809 together with brain training improves mental abilities. Participants take study medication once a day for 12 weeks. At the start of the study, the participants are put into 2 groups. It is decided …

antidepressants
anticholinergics
antipsychotics
clozapine
cognitive training
Atria Clinical Research
 (8.3 away) Contact site
  • 773 views
  • 15 Jun, 2021
  • +58 other locations
Assessing the Impact of Lipoprotein (a) Lowering With TQJ230 on Major Cardiovascular Events in Patients With CVD

This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)

Novartis Investigative Site
 (6.9 away) Contact site
  • 130 views
  • 05 Jun, 2021
  • +498 other locations
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

dabigatran
apixaban
anticoagulation therapy
antiplatelet therapy
fibrillation
CHI St. Vincent, Arkansas
 (4.6 away) Contact site
  • 112 views
  • 15 Jun, 2021
  • +78 other locations
A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study will last about 12 months and may include up to 7 visits.

lasmiditan
migraine in children
acute treatment
ly573144
University of Arkansas for Medical Sciences
 (2.9 away) Contact site
  • 129 views
  • 16 Jun, 2021
  • +236 other locations
Long-term Safety and Efficacy Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis (ADjoin)

This 110-week study is designed to assess the long-term safety and efficacy of lebrikizumab for moderate-to-severe atopic dermatitis.

topical agents
progestogen
atopy
lebrikizumab
eczema
Arkansas Skin Cancer Center - Little Rock
 (5.1 away) Contact site
  • 154 views
  • 16 Jun, 2021
  • +344 other locations
PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

Currently, warfarin is the only approved anticoagulation for patients with mechanical valves. The purpose of this study is to determine if participants with an On-X Prosthetic Heart Valve / On-X aortic valve can be maintained safely and effectively on apixaban. Both the On-X aortic valve and apixaban have been approved …

aspirin
warfarin
apixaban 5 mg
CHI St. Vincent Heart Institute
 (5.1 away) Contact site
  • 79 views
  • 17 Jun, 2021
  • +72 other locations
Linaclotide Safety and Efficacy in Pediatric Participants 6 to 17 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)

The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 g daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria for Child/Adolescent FC. The objective of LIN-MD-64 is to evaluate the …

posturing
incontinence
laxative
Applied Research Center of Arkansas
 (8.4 away) Contact site
  • 136 views
  • 05 Jun, 2021
  • +152 other locations
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Patients 6 to 17 Years of Age

The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of chronic migraine (CM). Secondary objectives are to further demonstrate the efficacy of Fremanezumab as compared to placebo for the preventive treatment of CM, to evaluate the safety and …

chronic migraine
headache
recurrent headaches
daily headaches
fremanezumab
Teva Investigational Site 14281
 (2.9 away) Contact site
  • 0 views
  • 16 Jun, 2021
  • +58 other locations