North Little Rock, Arkansas Clinical Trials

A listing of North Little Rock, Arkansas clinical trials actively recruiting patient volunteers.

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Found 9 clinical trials
The Hemophilia Inhibitor Prevention Trial

This is a multi-center randomized phase III clinical trial, the Inhibitor Prevention Trial, in which Eloctate will be compared with Emicizumab, using adaptive design, to prevent inhibitors in patients with severe hemophilia A.

University of Arkansas Medical Sciences Childrens Hospital
 (2.9 away) Contact site
  • 0 views
  • 15 Jun, 2021
  • +2 other locations
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency. The intention of the study is to demonstrate that in participants with mHSPC, the …

Research Site
 (4.6 away) Contact site
  • 109 views
  • 13 Jun, 2021
  • +263 other locations
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for …

University of Arkansas for Medical Sciences
 (4.6 away) Contact site
  • 247 views
  • 13 Jun, 2021
  • +298 other locations
Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201) a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered Non-infectious Virus (AAV) as a "Shuttle".

In this study researchers want to gather more information about safety and effectiveness of BAY 2599023 (DTX201), a drug therapy that delivers the human factor VIII gene into the human body by use of a viral vector to treat the disease. By replacing the defective gene with a healthy copy …

antihemophilic factor
coagulation factor
severe haemophilia a
bleeding tendency
Arkansas Children's Hospital
 (2.9 away) Contact site
  • 203 views
  • 12 Jun, 2021
  • +34 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

replacement therapy
testosterone level
testosterone
serum testosterone
testosterone topical
B.G. Clinical Research Center, LLC /ID# 170461
 (4.6 away) Contact site
  • 16823 views
  • 18 Jun, 2021
  • +434 other locations
A Phase 3 Trial of Pamrevlumab or Placebo in Combination With Systemic Corticosteroids in Subjects With Non-ambulatory Duchenne Muscular Dystrophy (DMD)

To evaluate the efficacy and safety of pamrevlumab versus placebo in combination with systemic corticosteroids in subjects with non-ambulatory Duchenne muscular dystrophy (age 12 years and older).

serum electrolyte
duchenne muscular dystrophy
potassium
ejection fraction
gamma glutamyl transferase
Arkansas Children's
 (2.9 away) Contact site
  • 60 views
  • 16 Jun, 2021
  • +26 other locations
Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Patients With Severe Hemophilia A or B

Treatment with PF-06741086 is anticipated to demonstrate a clinically relevant advantage and/or a major contribution to patient care in comparison to current methods of treatment for hemophilia A or B because it works differently than factor replacement products and will work in the presence of inhibitors. The potential for once …

acute hemorrhage
Factor VIII
acute bleeding
antihemophilic factor
severe haemophilia a
Arkansas Children's Hospital
 (2.3 away) Contact site
  • 58 views
  • 17 Jun, 2021
  • +73 other locations
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

The purpose of the study is to evaluate the safety and efficacy of talazoparib in combination with enzalutamide compared with placebo in combination with enzalutamide in participants with DDR-deficient mCSPC.

Arkansas Urology Research Clinic
 (4.0 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +12 other locations
A Phase 3 Trial of Pamrevlumab (FG-3019) or Placebo in Combination With Systemic Corticosteroids in Ambulatory Subjects With Duchenne Muscular Dystrophy (DMD)

To evaluate the efficacy and safety of pamrevlumab versus placebo in combination with systemic corticosteroids administered every two weeks in ambulatory subjects with Duchenne muscular dystrophy (age 6 to <12 years).

calcium
corticosteroids
prednisolone
serum electrolyte
duchenne muscular dystrophy
Arkansas Children's Hospital
 (2.3 away) Contact site
  • 0 views
  • 10 Jun, 2021
  • +7 other locations