Fayetteville, Arkansas Clinical Trials

A listing of Fayetteville, Arkansas clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 27 clinical trials
Study of AZD2811 + Durvalumab in ES-SCLC

A Phase II Multicenter, Open-Label, Single Arm Study to Determine the Efficacy, Safety and Tolerability of AZD2811 and Durvalumab Combination as Maintenance Therapy After Induction with Platinum-Based Chemotherapy Combined with Durvalumab, for the First-Line Treatment of Patients with Extensive Stage Small-Cell Lung Cancer

maintenance therapy
platinum-based chemotherapy
etoposide
cancer chemotherapy
carboplatin
Research Site
 (1.2 away) Contact site
  • 1 views
  • 12 Sep, 2021
  • +37 other locations
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

The study will evaluate the efficacy and safety of trastuzumab deruxtecan (also known as T-DXd, DS-8201a), either alone or in combination with pertuzumab, in treating patients with Human epidermal growth factor receptor 2 (HER2)-positive breast cancer as a first line of treatment.

Research Site
 (6.3 away) Contact site
  • 2 views
  • 11 Sep, 2021
  • +224 other locations
A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer

The main purpose of this study is to measure how well abemaciclib works in participants with early breast cancer who are taking hormone therapy after surgery. Participants must have breast cancer that is hormone receptor positive (HR+) and human epidermal receptor 2 positive (HER2+). Your participation could last up to …

HER2
hormone therapy
invasive breast cancer
pertuzumab
trastuzumab
Highlands Oncology Group
 (6.3 away) Contact site
  • 0 views
  • 12 Sep, 2021
  • +566 other locations
Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD Trial)

The purpose of the study is to assess efficacy, safety and tolerability of treatment with zibotentan and dapagliflozin in combination and alone, compared with placebo in participants with chronic kidney disease (CKD) with estimated glomerular filtration rate (eGFR) between 20 and 60 mL/min/1.73^2.

Research Site
 (1.2 away) Contact site
  • 19 views
  • 15 Sep, 2021
  • +151 other locations
UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

UV1 is a therapeutic cancer vaccine that has been explored in prostate, lung cancer, in combination with ipilimumab in malignant melanoma and in combination with pembrolizumab in metastatic melanoma. This study will explore the Efficacy and Safety of UV1 administered with GM-CSF in combination with nivolumab and ipilimumab.

vaccination
ipilimumab
platelet count
cancer
neutrophil count
Highlands Oncology Group
 (7.8 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +38 other locations
Pivotal Randomized Open-label Study of Optune (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

To test the effectiveness and safety of Optune given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune and maintenance temozolomide are continued following radiation therapy.

tumor progression
MRI
gross total resection
cancer
temozolomide
Highland Oncology Group
 (1.2 away) Contact site
  • 25 views
  • 02 Sep, 2021
  • +161 other locations
Study of TSR-042 an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody in Participants With Advanced Solid Tumors

This is a multi-center, open-label, first-in-human Phase 1 study evaluating the anti-programmed death receptor 1 (anti-PD-1) antibody dostarlimab (also known as TSR-042) n participants with advanced solid tumors who have limited available treatment options. The study will be conducted in 2 parts with Part 1 consisting of safety evaluation, pharmacokinetics …

primary cancer
sarcoma
treatment regimen
solid tumor
solid neoplasm
GSK Investigational Site
 (7.8 away) Contact site
  • 0 views
  • 03 Sep, 2021
  • +187 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

solid tumour
androgen
cns disease
adenosarcoma
pituitary
Highlands Oncology Group PA - Fayetteville
 (1.2 away) Contact site
  • 6048 views
  • 15 Sep, 2021
  • +817 other locations
Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of IIIB (T>5cm N2 disease) completely resected (R0) non-small cell lung cancer (NSCLC).

alopecia
lung carcinoma
systemic therapy
Highlands Oncology Group
 (7.8 away) Contact site
  • 645 views
  • 16 Sep, 2021
  • +416 other locations
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel. In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or …

Highlands Oncology Group /ID# 201568
 (6.3 away) Contact site
  • 542 views
  • 15 Sep, 2021
  • +46 other locations