Fayetteville, Arkansas Clinical Trials

A listing of Fayetteville, Arkansas clinical trials actively recruiting patient volunteers.

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Found 24 clinical trials
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low Hormone Receptor Positive Metastatic Breast Cancer

This study will evaluate the efficacy, safety and tolerability of trastuzumab deruxtecan compared with investigator's choice chemotherapy in human epidermal growth factor receptor (HER)2-low, hormone receptor (HR) positive breast cancer patients whose disease has progressed on endocrine therapy in the metastatic setting.

Research Site
 (6.3 away) Contact site
  • 35 views
  • 23 Jun, 2021
  • +245 other locations
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

The purpose of this study is to compare the immunogenicity and describe the safety of MenACYW conjugate vaccine and MENVEO when both are administered concomitantly with routine pediatric vaccines to healthy infants and toddlers in the US. Primary objectives: To demonstrate the non-inferiority of the immune response after a 4-dose …

hib vaccine
measles
conjugate vaccine
hepatitis b
menveo
Investigational Site Number 8400011
 (1.2 away) Contact site
  • 501 views
  • 14 Jun, 2021
  • +83 other locations
Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer

This study is designed to identify the target Non-Small Cell Lung Cancer (NSCLC) population(s) that over express c-Met (c-Met+) best suited for telisotuzumab vedotin therapy in the second line or third line setting (Stage 1) and then to expand the group(s) to further evaluate efficacy in the selected population(s) (Stage …

systemic therapy
tyrosine
epidermal growth factor receptor
growth factor
stage iv non-small cell lung cancer
Highlands Oncology Group /ID# 215600
 (6.3 away) Contact site
  • 118 views
  • 23 Jun, 2021
  • +302 other locations
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel. In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or …

Highlands Oncology Group /ID# 201568
 (6.3 away) Contact site
  • 542 views
  • 21 Jun, 2021
  • +45 other locations
A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations

The purpose of this study is to evaluate the efficacy of erdafitinib in terms of overall response rate (ORR) in participants with advanced solid tumors with fibroblast growth factor receptor (FGFR) mutations and gene fusions.

solid tumour
cancer
growth factor
measurable disease
Highlands Oncology Group
 (1.2 away) Contact site
  • 33 views
  • 23 Jun, 2021
  • +265 other locations
A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer

The reason for this study is to see if the study drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in participants with advanced or metastatic breast cancer or endometrial cancer.

cancer
immunostimulant
growth factor
exemestane
her2-negative breast cancer
Highlands Oncology Group
 (7.8 away) Contact site
  • 58 views
  • 23 Jun, 2021
  • +92 other locations
UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

UV1 is a therapeutic cancer vaccine that has been explored in prostate, lung cancer, in combination with ipilimumab in malignant melanoma and in combination with pembrolizumab in metastatic melanoma. This study will explore the Efficacy and Safety of UV1 administered with GM-CSF in combination with nivolumab and ipilimumab.

cancer
nivolumab
vaccination
ipilimumab
immunologic adjuvant
Highlands Oncology Group
 (7.8 away) Contact site
  • 0 views
  • 22 Jun, 2021
  • +34 other locations
Study of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA Mutation

The purpose of this two parts multicenter, randomized, double-blind, placebo-controlled, Phase III study is to evaluate the efficacy and safety of alpelisib compared to alpelisib matching-placebo in combination with trastuzumab and pertuzumab as maintenance treatment of patients with HER2-positive advanced breast cancer whose tumor harbors a PIK3CA mutation following induction …

Highlands Oncology Group
 (7.8 away) Contact site
  • 0 views
  • 15 Jun, 2021
  • +16 other locations
Safety and Immunogenicity Study of 20vPnC in Healthy Children 15 Months Through 17 Years of Age

This study is designed to evaluate the safety and immunogenicity of 20vPnC in healthy children 15 months through 17 years of age

conjugate vaccine
pneumococcal conjugate
Northwest Arkansas Pediatrics
 (1.2 away) Contact site
  • 0 views
  • 23 Jun, 2021
  • +46 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

mini-mental state examination
positron emission tomography
flortaucipir
alzheimer's disease
florbetapir
Health Initiatives Research
 (1.2 away) Contact site
  • 79 views
  • 20 Jun, 2021
  • +384 other locations