Fayetteville, Arkansas Clinical Trials

A listing of Fayetteville, Arkansas clinical trials actively recruiting patient volunteers.

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Found 29 clinical trials
A Randomized Phase 3 Study of MRTX849 in Combination with Cetuximab Versus Chemotherapy in Patients with Advanced Colorectal Cancer with KRAS G12C Mutation with Disease Progression On or After Standard First-Line Therapy (KRYSTAL-10)

Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus chemotherapy in the second-line treatment setting in patients with CRC with KRAS G12C mutation.

Highlands Oncology Group - Springdale
 (7.5 away) Contact site
  • 16 Jun, 2021
  • +17 other locations
Long Term Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2 Study 12-AVR-131 to be included.

Health Initiatives Research
 (1.2 away) Contact site
  • 04 Jun, 2021
  • +296 other locations
Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study

The rollover study will provide ceritinib to patients who are currently receiving treatment with ceritinib within a Novartis-sponsored study and in the opinion of the investigator, would benefit from continued treatment with ceritinib.

Highlands Oncology Group
 (1.2 away) Contact site
  • 03 Jun, 2021
  • +2 other locations
Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC)

This is a Phase III, randomized, parallel-arm, placebo controlled, double blind, multicenter study assessing the efficacy and safety of durvalumab versus placebo following SoC chemotherapy in patients with completely resected stage II-III NSCLC who are MRD+ post surgery

lung carcinoma
cancer chemotherapy
Research Site
 (1.2 away) Contact site
  • 02 Jun, 2021
  • +241 other locations
Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of IIIB (T>5cm N2 disease) completely resected (R0) non-small cell lung cancer (NSCLC).

lung carcinoma
systemic therapy
Highlands Oncology Group
 (7.8 away) Contact site
  • 03 Jun, 2021
  • +406 other locations
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

The purpose of this study is to compare the immunogenicity and describe the safety of MenACYW conjugate vaccine and MENVEO when both are administered concomitantly with routine pediatric vaccines to healthy infants and toddlers in the US. Primary objectives: To demonstrate the non-inferiority of the immune response after a 4-dose …

hib vaccine
varicella vaccine
Investigational Site Number 8400011
 (1.2 away) Contact site
  • 14 Jun, 2021
  • +83 other locations
Diuretic Comparison Project

The purpose of this study is to determine whether chlorthalidone is more effective than hydrochlorothiazide at preventing cardiovascular outcomes in Veterans over age 65 with hypertension. Both medications are thiazide-type diuretics that have been used for more than 50 years and are considered first-line treatment for hypertension. Patients currently prescribed …

systolic blood pressure
myocardial infarction
Veterans Health Care System of the Ozarks, Fayetteville, AR
 (1.2 away) Contact site
  • 16 Jun, 2021
  • +63 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

mucinous adenocarcinoma
desmoid tumors
squamous cell carcinoma of the head and neck
undifferentiated carcinoma
Highlands Oncology Group PA - Fayetteville
 (1.2 away) Contact site
  • 16 Jun, 2021
  • +812 other locations
Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

This study is to help determine the most effective type or combination of treatments to offer patients seeking lung cancer screening who are smokers to help them reduce the number of cigarettes they smoke, or quit smoking. The investigators long term goal is to increase the benefits of lung cancer …

nicotine replacement
tobacco smoke
cigarette smoke
nicotine lozenge
Highlands Oncology Group
 (7.8 away) Contact site
  • 12 Jun, 2021
  • +18 other locations
Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors

This study is to assess the safety and tolerability, and to assess the preliminary clinical benefit of NKTR-214 when combined with pembrolizumab (KEYTRUDA) with or without chemotherapy. The study is comprised of two groups; dose optimization and dose expansion cohorts. Dose Optimization will include first-line and second-line melanoma, non-small cell …

lung cancer
measurable disease
solid tumour
Investigator Site- Fayetteville
 (7.8 away) Contact site
  • 04 Jun, 2021
  • +66 other locations