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Northwick Park, United Kingdom Clinical Trials

A listing of Northwick Park, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (80) clinical trials

Study to Assess Effect of Device and Formulation on Pharmacokinetics (PK) of AZD1402

This study will be a randomized, open-label, 3-period, 3-treatment, single dose, single-center, crossover study. Eighteen healthy male and female subjects will be randomized in this study to ensure that at least 12 subjects are evaluable. A subject will be considered to be evaluable if the subject completes all 3 Treatment ...

Phase

0.12 miles

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Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

This is a Phase 1 study of BION-1301, a first-in-class humanized IgG4 anti-a proliferation-inducing ligand (APRIL) monoclonal antibody. The study will be conducted in three parts. Part 1: double-blind, randomized, placebo-controlled, single ascending dose (SAD) in healthy volunteers (HVs). Part 2: double-blind, randomized, placebo-controlled multiple ascending dose (MAD) in HVs. ...

Phase

0.12 miles

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A Study in Healthy Volunteers and Patients With Mild Asthma to Investigate the Safety Anti-inflammatory Effect of Inhaled AZD0449.

Part 1a of the study with six inhaled dose levels of AZD0449 nebulized suspension are planned to be investigated in 6 cohorts. Depending on emerging safety and PK data, up to 3 additional inhaled dose levels (cohorts), within the pre-specified dose range may be added at the discretion of the ...

Phase

0.12 miles

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Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects

This study will be an open-label, randomized, 3-period, 3-treatment, single-dose crossover study in healthy subjects (males and females), performed at a single study center, conducted in 3 cohorts. A total of 126 healthy male or female subjects (3 cohorts of 42 subjects each [each cohort consisting of 3 treatments]) will ...

Phase

0.13 miles

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A Phase I Study to Assess the Safety Tolerability Pharmacokinetics Pharmacodynamics and Food Effect of AZD9898

This study will be a Phase I, randomized, placebo-controlled study in healthy subjects and asthma patients, performed at 2 study centers. The study will consist of 3 parts (Part 1 [SAD in healthy subjects]; Part 2 [SAD in asthma patients]; Part 3 [MAD in healthy subjects under fasted conditions, with ...

Phase

0.13 miles

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A First Time in Human Study of PIN201104 in Healthy Volunteers and Patients With Asthma

The purpose of this study is to assess the safety, tolerability and pharmacokinetics of different single and repeat doses of PIN201104 in healthy volunteers and in patients with asthma.

Phase

1.03 miles

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A Two-Part Study to Assess the Safety Tolerability PK and PD of ONO-7684 in Healthy Adult Volunteers

This study aims to obtain safety, tolerability, pharmacokinetic and pharmacodynamic data when ONO-7684 is administered orally as single doses and as multiple doses to healthy subjects. The study will consist of 2 parts: A single ascending dose (SAD) phase (Part A); a multiple ascending dose (MAD) phase (Part B). One ...

Phase

3.56 miles

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Safety Tolerability & Pharmacokinetics of LEVI-04 in Healthy Volunteers and Patients With Osteoarthritis Knee Pain

There will be 8 cohorts of 7 subjects each. Cohorts 1-3 will be composed of healthy volunteers. Cohorts 4-8 will be composed of osteoarthritis patients. Cohort 4 will be a bridging cohort; osteoarthritis patients in Cohort 4 will receive the same dose as the healthy volunteers in Cohort 3, if ...

Phase

3.59 miles

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Assessment of Pharmacokinetics (PK) and Safety of M834 and Orencia in Healthy Subjects

The purpose of this study is assess the pharmacokinetics and safety of M834 and Orencia ® following administration of a single-dose in healthy volunteers.

Phase

3.59 miles

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First in Man Clinical Trial of Emodepside (BAY 44-4400)

This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers. This study will also conduct an exploratory investigation of the relative bioavailability of emodepside administered as tablets.

Phase

3.59 miles

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