Hardwick,, United Kingdom Clinical Trials

A listing of Hardwick,, United Kingdom clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 219 clinical trials
A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease.

The study is intended to show superiority of AZD9833 in combination with palbociclib (a CDK4/6 inhibitor) versus anastrozole (an aromatase inhibitor) and palbociclib as the initial treatment of patients with hormone receptor-positive (ER-positive), human epidermal growth factor 2-negative (HER2-negative) advanced/metastatic breast cancer.

Research Site
 (6.1 away) Contact site
  • 0 views
  • 06 Sep, 2021
  • +206 other locations
Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults

This Phase III study will assess whether AZD7442 (a combination of 2 mAbs) can safely treat outpatient adults with COVID-19 and prevent either severe COVID-19 or death.

Research Site
 (6.1 away) Contact site
  • 1 views
  • 09 Jul, 2021
  • +128 other locations
Sample Collection Study to Aid Evaluation of an Influenza A/B Respiratory Syncytial Virus & COVID-19 Virus POC Test

Collection of Nasal Swabs, Throat Swabs and Saliva Samples from patients presenting at their designated care or testing facility displaying symptoms of either Influenza, Respiratory Syncytial Virus (RSV), SARS-CoV-2 or those who have been in recent contact with SARS-CoV-2 positive patients. Collected samples will aid the development, calibration and performance …

Cambridge University Hospitals NHS Foundation Trust
 (4.1 away) Contact site
  • 0 views
  • 13 Mar, 2021
  • +5 other locations
A Study of Ponatinib With Chemotherapy in Children Teenagers and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

This study is about an anticancer drug called ponatinib which is a tyrasine kinase inhibitor given with chemotherapy to children, teenagers, and young adults up to 21 years of age with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia who have relapsed or are resistant to other treatment. The main aims of this …

Cambridge University Hospitals NHS Foundation Trust
 (4.1 away) Contact site
  • 2 views
  • 13 Aug, 2021
  • +63 other locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The purpose of this study is to evaluate: a) the efficacy of ustekinumab dosing in inducing clinical remission, b) safety profile of ustekinumab, and c) ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with moderately to severely active UC.

remission
endoscopy
Cambridge University Hospitals NHS Foundation Trust
 (4.1 away) Contact site
  • 0 views
  • 11 Sep, 2021
  • +57 other locations
Ponto Implantation Using a Minimally Invasive Surgical Technique

This multi-centre study funded by Oticon Medical AB will be conducted at seven hospitals across Europe (UK, Sweden, Denmark and the Netherlands). In total, 50 adult patients with a hearing loss that are already planned for treatment with a percutaneous (through the skin) bone-anchored hearing system (BAHS) will be included …

audiogram
hard of hearing
Cambridge University Hospitals NHS Foundation Trust
 (4.1 away) Contact site
  • 6 views
  • 19 Aug, 2021
  • +7 other locations
Dapagliflozin Effects on Cardiovascular Events in Patients With an Acute Heart Attack

This study will evaluate the effect of dapagliflozin versus placebo, given once daily in addition to Standard of Care (SoC) therapies for patients with myocardial infarction (MI), for the prevention of hospitalisation for heart failure (HHF) or cardiovascular (CV) death.

ventriculogram
ejection fraction
cardiac mri
MRI
heart failure
Research Site
 (6.1 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +91 other locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at …

vedolizumab
tumor necrosis factor alpha
ustekinumab
maintenance treatment
immunomodulators
Cambridge University Hospital NHS Foundation Trust
 (4.8 away) Contact site
  • 12 views
  • 22 Sep, 2021
  • +555 other locations
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on cognitive decline using the Alzheimer's Disease Assessment Scale Cognitive subscale 13-item version (ADAS-Cog13).

dementia
cognitive decline
alzheimer's disease
cognitive assessment
Fulbourne Hospital
 (7.7 away) Contact site
  • 3 views
  • 07 Sep, 2021
  • +148 other locations
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer

DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with other anti-cancer agents in patients with HER2-positive Metastatic Breast Cancer

Research Site
 (6.1 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • +74 other locations