Hardwick,, United Kingdom Clinical Trials

A listing of Hardwick,, United Kingdom clinical trials actively recruiting patients volunteers.

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Found 219 clinical trials
Paediatric Hepatic International Tumour Trial

The PHITT trial is an over-arching study for patients with Hepatoblastoma (HB) and Hepatocellular Carcinoma (HCC). This trial will use a risk-adapted approach to the treatment of children diagnosed with HB. Children with HCC will be included as a separate cohort.

etoposide
sorafenib
oxaliplatin
vincristine
carboplatin
Addenbrooke's Hospital
 (6.1 away) Contact site
  • 38 views
  • 27 Jan, 2021
  • +1 other locations
Cambridge Brain Mets Trial 1

Proof of principle phase 1b / randomised phase 2 study of afatinib penetration into cerebral metastases for patients undergoing neurosurgical resection, both with and without prior low-dose, targeted radiotherapy.

hormone therapy
corticosteroids
brain metastases
cancer
afatinib
Cambridge University Hospitals NHS Foundation Trust
 (4.5 away) Contact site
  • 0 views
  • 03 Feb, 2021
  • +5 other locations
Proof-of-Concept Trial on Selective Removal of sFlt-1 in Pregnant Women With Preeclampsia Via Apheresis

This clinical investigation is a medical device trial to examine the safety and efficacy of TheraSorb sFlt-1 adsorber treatment of pregnant patients with preeclampsia.

Cambridge Clinical Trials Unit, Addenbrooke's Hospital
 (6.1 away) Contact site
  • 86 views
  • 02 Aug, 2021
  • +7 other locations
Minimal Access Repair of Contralateral Hernias (MARCH Trial)

Repair of unilateral inguinal hernia in infants. Laparoscopic repair, with closure of contralateral patent processus vaginalis if present, versus open repair

Addenbrookes Hospital
 (4.8 away) Contact site
  • 29 views
  • 07 Nov, 2020
  • 1 location
Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension

Can the oral glucose tolerance test detect changes after 4 weeks treatment with thiazide diuretics or beta blockers or combination of the two?

Clinical Pharmacology Unit, Box 110, Level 3 ACCI, Addenbrookes Hospital
 (4.5 away) Contact site
  • 0 views
  • 07 Nov, 2020
  • 1 location
Double Blind Crossover Comparison of Diuretics in the Young

The principle objective of the study is to determine whether low-renin (i.e. salt sensitive) hypertension at a young age is caused by the kidneys hanging onto too much salt as a result of an over active salt pump in the kidney. The kidneys have four different salt pumps, and each …

University of Cambridge - Addenbrookes Hospital
 (4.5 away) Contact site
  • 0 views
  • 07 Nov, 2020
  • 1 location
Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer

RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, fluorouracil, leucovorin, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability …

oxaliplatin
leucovorin
liver metastasis
calcium
adjuvant chemotherapy
Addenbrooke's Hospital
 (6.1 away) Contact site
  • 98 views
  • 07 Nov, 2020
  • +7 other locations
Mesothelioma and Radical Surgery 2

Mesothelioma is a cancer of the thin membrane that lines the chest and abdomen. Around 2500 people in the UK are diagnosed with mesothelioma each year and the median survival is approximately 8.5 months. Exposure to asbestos is the most common cause although the cancer does not usually become apparent …

asbestos exposure
pleurectomy
cancer
chemotherapy regimen
Papworth
 (4.8 away) Contact site
  • 151 views
  • 23 Jan, 2021
  • +23 other locations
Stereotactic Ablative Radiotherapy for Oligometastatic Non-small Cell Lung Cancer

The trial will assess the addition of stereotactic ablative radiotherapy (SABR) to standard anti-cancer therapy (SACT) in patients with oligometastatic non-small cell lung cancer. Patients will be randomised to receive either standard treatment alone (SACT) or standard treatment with conventional radiotherapy (RT) and SABR.

lung carcinoma
metastasis
brain metastases
stereotactic body radiation therapy
cancer treatment
Addenbrooke's Hospital
 (4.8 away) Contact site
  • 62 views
  • 25 Jan, 2021
  • +18 other locations