Dundee, United Kingdom Clinical Trials

A listing of Dundee, United Kingdom clinical trials actively recruiting patients volunteers.

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Found 51 clinical trials
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

Research Site
 (0.8 away) Contact site
  • 0 views
  • 15 May, 2021
  • +96 other locations
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will either get semaglutide or a dummy medicine - which treatment participants get is decided by chance. Participants will need to …

Novo Nordisk Investigational Site
 (0.8 away) Contact site
  • 0 views
  • 21 Jun, 2021
  • +246 other locations
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the selected dose regimen in participants with metastatic or surgically unresectable urothelial cancers that harbor specific FGFR genomic alterations.

adjuvant chemotherapy
measurable disease
erdafitinib
renal function
dose regimen
Ninewells Hospital
 (0.8 away) Contact site
  • 40 views
  • 29 May, 2021
  • +150 other locations
Single Palatal Temporary Anchorage Device for Anterior Open Bite

Participants are orthodontic patients with anterior open bite (AOB) malocclusion. These patients will be treated by molar intrusion achieved using one of two interventions, either orthodontic fixed appliances incorporating a single palatal Temporary Anchorage Device (TAD) or orthodontic fixed appliances incorporating two buccal TADs

Dundee Dental Hospital
 (0.4 away) Contact site
  • 0 views
  • 02 May, 2021
  • 1 location
Study of Safety Tolerability Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in patients with bronchiectasis will demonstrate clinical safety and efficacy related to improved mucociliary clearance with reduced bacterial colonization as potential drivers of airway obstruction, reduced airway inflammation, exacerbations and mucus …

spirometry
grip
cystic fibrosis
combinations
macrolides
Novartis Investigative Site
 (0.8 away) Contact site
  • 0 views
  • 19 Jun, 2021
  • +5 other locations
Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR)

Patients with bronchiectasis (BE) suffer from a persistent cough, daily sputum expectoration, recurrent chest infections, and a poor health-related quality of life. Current guidelines for the management of BE highlight the lack of evidence to recommend mucoactive agents, such as hypertonic saline (HTS) and carbocisteine, to aid sputum-removal as part …

Royal Infirmary Edinburgh, NHS Lothian
 (36.0 away) Contact site
  • 0 views
  • 23 Jan, 2021
  • +10 other locations
Value of Inhaled Treatment With Aztreonam Lysine in Bronchiectasis

A randomised controlled trial of the safety, tolerability and effectiveness of 2 doses of Cayston (Aztreonam Lysine) compared to placebo in participants with bronchiectasis. Bronchiectasis not due to cystic fibrosis is a chronic inflammatory disease characterised by cough, sputum production and frequent respiratory tract infections. There are currently no licensed …

NHS Tayside
 (0.8 away) Contact site
  • 7 views
  • 15 Feb, 2021
  • +5 other locations
Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

The main objective of this study is to evaluate the efficacy of SZC as compared with placebo in keeping potassium levels within the normal range (3.5-5.0 mEq/L) while on spironolactone 25 mg daily without assistance of rescue therapy for hyperkalaemia (HK).

Research Site
 (0.8 away) Contact site
  • 0 views
  • 24 May, 2021
  • +36 other locations
Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

This is a multicenter, randomized, placebo-controlled, 2-part study to evaluate the safety and efficacy of AT-001 in adult patients (N=675) with Diabetic Cardiomyopathy at high risk of progression to overt heart failure.

heart failure
nt-probnp
Ninewells Hospital & Medical School
 (0.8 away) Contact site
  • 0 views
  • 21 Jun, 2021
  • +79 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

endoscopy
mirikizumab
Ninewells Hospital
 (0.8 away) Contact site
  • 386 views
  • 20 Jun, 2021
  • +903 other locations