Dundee, United Kingdom Clinical Trials

A listing of Dundee, United Kingdom clinical trials actively recruiting patients volunteers.

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Found 64 clinical trials
A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)

Recombinant human parathyroid hormone, also known as if rhPTH(1-84), is a medicine to treat people with Hypothyroidism. The main aim of this study is to learn if rhPTH(1-84) can improve symptoms in adults with hypoparathyroidism. In this study, participants will receive 1 of 2 treatments: rhPTH(1-84) or a placebo. A …

replacement therapy
parathyroid hormone
calcitriol
vitamin
tsh level
Ninewells Hospital - PPDS
 (0.8 away) Contact site
  • 200 views
  • 03 Feb, 2021
  • +49 other locations
A Phase 3 Efficacy Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer

A study of zolbetuximab (IMAB362) plus mFOLFOX6 versus placebo plus mFOLFOX6 in subjects with Claudin 18.2 positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical study for adult patients who have any of: advanced unresectable gastric …

Site GB44104
 (2.8 away) Contact site
  • 484 views
  • 23 Jul, 2021
  • +237 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

endoscopy
mirikizumab
Ninewells Hospital
 (0.8 away) Contact site
  • 386 views
  • 26 Jul, 2021
  • +906 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

body mass index
overweight or obesity
cardiovascular disease
Novo Nordisk Investigational Site
 (0.8 away) Contact site
  • 7721 views
  • 18 Jul, 2021
  • +1164 other locations
Precision-Panc Master Protocol: Personalising Treatment for Pancreatic Cancer

The Precision-Panc Master Protocol is a "portal" protocol for patients with known or suspected pancreatic cancer to be accrued through multiple centres in the UK, with the option of being subsequently enrolled into PRIMUS (Pancreatic canceR Individualised Multi-arm Umbrella Studies) examining different treatment regimens and/or biomarker development. Eligible patients will …

breast ductal carcinoma
cancer chemotherapy
adenocarcinoma
pancreatic ductal adenocarcinoma
metastasis
Western General
 (36.0 away) Contact site
  • 23 views
  • 26 Jan, 2021
  • +21 other locations
Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial

MND-SMART is investigating whether selected drugs can slow down the progression of motor neurone disease (MND) and improve survival. The study is 'multi-arm' meaning more than one treatment will be tested at the same time. In the first instance the trial will have 3 arms; drug 1, drug 2 and …

atrophy
memantine
neurodegenerative disorders
motor neuron disease
primary lateral sclerosis
Anne Rowling Regenerative Neurology Clinic
 (37.7 away) Contact site
  • 8 views
  • 03 Jul, 2021
  • +7 other locations
The British Heart Foundation SENIOR-RITA Trial

SENIOR-RITA is a multicentre prospective open-label trial randomizing patients presenting with type 1 NSTEMI aged 75 years between invasive and conservative treatment strategies, to compare time to cardiovascular death or non-fatal MI within one year from randomization.

coronary revascularization
angiography
stemi
medical therapy
Ninewells Hospital, NHS Tayside
 (0.8 away) Contact site
  • 294 views
  • 25 Jan, 2021
  • +41 other locations
Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

ICON 9 will assess the efficacy, safety and tolerability of maintenance olaparib in combination with cediranib compared to maintenance olaparib alone following a response to platinum-based chemotherapy in women with relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer. Prognostic and predictive factors will be studied from tumour and blood samples.

parp inhibitor
cancer antigen 125
carcinoma
peritoneal cancer
tumor debulking
Ninewells Hospital
 (0.8 away) Contact site
  • 392 views
  • 01 Aug, 2021
  • +45 other locations
Steroid Withdrawal Intervention in Fife and Tayside

The SWIFT trial is a cluster randomised trial to determine if a patient identification, feedback and inhaled corticosteroid (ICS) withdrawal intervention in primary care can result in more appropriate inhaled corticosteroid use without increasing the frequency of exacerbations. Practices in Tayside and Fife will be randomised at practice level to …

muscarinic antagonists
corticosteroids
bronchodilator
NHS Tayside
 (0.8 away) Contact site
  • 37 views
  • 17 Mar, 2021
  • +1 other locations
Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trastuzumab in combination with SOC chemotherapy in participants with HER2-positive gastric cancer. The primary hypotheses of the study are that pembrolizumab plus trastuzumab in combination with chemotherapy is superior …

mk-3475
erbb2
EGFR
HER2
immunohistochemistry
Ninewells Hospital and Medical School ( Site 1504)
 (0.8 away) Contact site
  • 303 views
  • 02 Aug, 2021
  • +206 other locations