Zhytomyr, Ukraine Clinical Trials

A listing of Zhytomyr, Ukraine clinical trials actively recruiting patients volunteers.

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Found 28 clinical trials
Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)

The purpose of this study is to compare the efficacy of olaparib (MK-7339) plus pembrolizumab (MK-3475) with chemotherapy plus pembrolizumab after induction with first-line chemotherapy plus pembrolizumab in triple negative breast cancer (TNBC). The primary hypotheses are: Olaparib plus pembrolizumab prolongs progression-free survival (PFS) compared with chemotherapy plus pembrolizumab. Olaparib …

anthracyclines
measurable disease
cancer
triple negative breast cancer
carboplatin
Medical Center Verum ( Site 1501)
 (83.0 away) Contact site
  • 241 views
  • 26 Nov, 2020
  • +118 other locations
A Comparative Study Between PF-06410293 and Humira in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis

The study will assess the impact of pharmacokinetics (PK), safety and immunogenicity after switches between PF-06410293 and adalimumab and with continuous dosing with adalimumab in combination with methotrexate in subjects with moderately to severely active rheumatoid arthritis.

methotrexate
adalimumab
humira
Komunalne nekomertsiine pidpryiemstvo "Vinnytska oblasna klinichna likarnia im. M.I. Pyrohova
 (70.8 away) Contact site
  • 124 views
  • 08 Oct, 2020
  • +77 other locations
A Phase II Study in Patients With Moderate to Severe Active Crohn's Disease

The proposed study is a randomized, double-blind, placebo-controlled, multi-center Phase II study to investigate the safety and efficacy of SHR0302 in patients with moderate to severe active Crohn's Disease. The study aims to evaluate the optimal dose of SHR0302 and time needed in inducing clinical remission in active CD. This …

remission
crohn's disease
CCH #1 Vinnytsia M.I. Pyrogov NMU Ch of Propaedeutics of IM
 (70.8 away) Contact site
  • 72 views
  • 19 Nov, 2020
  • +80 other locations
A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

The study will enroll up to 60,000 participants in order to evaluate the efficacy of Ad26.COV2.S in the prevention of molecularly confirmed moderate to severe/critical COVID-19, as compared to placebo, in adult participants.

CCH #1 Vinnytsia M.I. Pyrogov NMU Ch of Propaedeutics of IM
 (70.8 away) Contact site
  • 1997 views
  • 20 Nov, 2020
  • +299 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

body mass index
overweight or obesity
cardiovascular disease
Novo Nordisk Investigational Site
 (70.8 away) Contact site
  • 7712 views
  • 29 Nov, 2020
  • +1155 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

diabetes
arterial disease
stemi
myocardial infarction
stroke
8040045 - Vinnitsa Regional Clinical Hospital im. N.I. Pirogov
 (70.8 away) Contact site
  • 1118 views
  • 25 Nov, 2020
  • +3405 other locations
A Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate Cancer

The purpose of this study is to evaluate the prevalence of 4 or more DNA-repair gene defects in a population of men with metastatic Prostate Cancer (PC) and to use the reported DNA-repair gene defects to assess biomarker eligibility for niraparib interventional studies.

metastasis
State Institution National Cancer Institute
 (83.0 away) Contact site
  • 652 views
  • 11 Nov, 2020
  • +301 other locations
A Study to Identify Participants With Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations

The purpose of this non-interventional study is to identify participants with urothelial cancer (UC) and selected fibroblast growth factor receptor (FGFR) aberrations through molecular testing of their archival tumor tissue.

transitional cell carcinoma
growth factor
carcinoma
State Institution Institute of Urology NAMS of Ukraine based on Kyiv City Clinical Oncology Center
 (83.0 away) Contact site
  • 111 views
  • 11 Nov, 2020
  • +213 other locations