Boadilla del Monte, Spain Clinical Trials

A listing of Boadilla del Monte, Spain clinical trials actively recruiting patients volunteers.

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Found 218 clinical trials
Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-LUNG01)

This study will evaluate the efficacy, safety, and pharmacokinetics of DS-1062a versus docetaxel in participants with previously treated advanced or metastatic non-small cell lung cancer (NSCLC) without actionable genomic alterations.

epidermal growth factor receptor
EGFR
lung carcinoma
tyrosine
measurable disease
Hospital Puerte de Hierro de Majadahonda
 (4.7 away) Contact site
  • 0 views
  • 17 Sep, 2021
  • +196 other locations
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902) or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib Versus Pembrolizumab and Lenvatinib for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

The goal of this study is to evaluate the efficacy and safety of pembrolizumab plus belzutifan plus lenvatinib or pembrolizumab/quavonlimab plus lenvatinib versus pembrolizumab plus lenvatinib as first-line treatment in participants with advanced clear cell renal cell carcinoma (ccRCC). The primary hypotheses are (1) pembrolizumab plus belzutifan plus lenvatinib is …

systemic therapy
lenvatinib
clear cell renal cell carcinoma
carcinoma
pembrolizumab
Hospital Clinico San Carlos ( Site 1503)
 (8.2 away) Contact site
  • 3 views
  • 15 Sep, 2021
  • +92 other locations
Study for Patients With Newly Diagnosed High-risk Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is a rare subtype of acute myeloid leukemia (AML) characterized by consistent clinical, morphologic, and genetic features. According to the FAB classification APL is designated as"M3 leukemia" and assigned to the WHO defined type of AML with recurrent cytogenetic abnormalities, "acute promyelocytic leukemia with t(15;17)(q22;q12), (PML/RAR) …

myeloid leukemia
acute promyelocytic leukemia
serum bilirubin
methotrexate
secondary mds
PETHEMA study group
 (8.1 away) Contact site
  • 0 views
  • 26 Aug, 2021
  • +7 other locations
Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Investigation of the efficacy and safety of a new potential treatment of Major depressive disorder (MDD) in paediatric patients (age 7 to 11 years)

vortioxetine
major depressive disorder
fluoxetine
Hospital Universitario Fundacion Alcorcon
 (4.2 away) Contact site
  • 2 views
  • 19 Jul, 2021
  • +280 other locations
A Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Received Stem Cell Transplants

This study is about treatment options for cytomegalovirus infections in people who have received stem cell transplants. The main aim of the study is to check if the cytomegalovirus infection can no longer be detected after treatment with marivabir or valganciclovir. Participants will take 2 tablets of marivabir or valganciclovir …

Hospital Universitario Puerta de Hierro - Majadahonda
 (4.7 away) Contact site
  • 746 views
  • 19 Jul, 2021
  • +137 other locations
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for …

systemic therapy
lung carcinoma
docetaxel
HGU Gregorio Mara n
 (9.7 away) Contact site
  • 644 views
  • 15 Sep, 2021
  • +178 other locations
Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of IIIB (T>5cm N2 disease) completely resected (R0) non-small cell lung cancer (NSCLC).

alopecia
systemic therapy
lung carcinoma
Novartis Investigative Site
 (4.7 away) Contact site
  • 645 views
  • 16 Sep, 2021
  • +416 other locations
Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)

The prevention of perioperative atrial fibrillation has the potential to reduce mortality, stroke, and hospital stays in patients undergoing thoracic surgery. Data from cardiac surgery patients suggest that prevention of perioperative atrial fibrillation using an anti-inflammatory agent, such as colchicine, is feasible. The COP-AF trial will assess whether the administration …

heart surgery
anti-inflammatory agent
fibrillation
colchicine
stroke
Hospital Ram n y Cajal
 (9.7 away) Contact site
  • 72 views
  • 10 Jul, 2021
  • +46 other locations
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who roll-over into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. …

pembrolizumab
major surgery
mk-3475
metastasis
Hospital Universitario Quiron Madrid ( Site 0868)
 (3.7 away) Contact site
  • 534 views
  • 15 Sep, 2021
  • +274 other locations
Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia

This study will evaluate the efficacy of uproleselan (GMI-1271), a specific E-selectin antagonist, in combination with chemotherapy to treat relapsed/refractory AML, compared to chemotherapy alone. The safety of uproleselan when given with chemotherapy will also be investigated in patients with relapsed/refractory AML

refractory acute myeloid leukemia (aml)
Hospital Universitario Fundaci n Jim nez Diaz
 (8.2 away) Contact site
  • 89 views
  • 08 Sep, 2021
  • +72 other locations