Boadilla del Monte, Spain Clinical Trials

A listing of Boadilla del Monte, Spain clinical trials actively recruiting patients volunteers.

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Found 30 clinical trials
Efficacy Safety and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.

This clinical study will test the effects of a drug called apremilast in oligoarticular psoriatic arthritis with less than 5 years of disease duration. In previous studies, apremilast has been shown to be safe and efficacious in reducing signs and symptoms of psoriatic arthritis, as well as improving physical function. …

Research Site
 (9.7 away) Contact site
  • 14 Jun, 2021
  • +267 other locations
A Study of the Safety and Efficacy of Risankizumab in Adult Participants With Plaque Psoriasis Who Have Had a Suboptimal Response to Secukinumab or Ixekizumab

This study will evaluate whether adult participants with moderate to severe plaque psoriasis who have been treated with secukinumab or ixekizumab for at least 6 months and are experiencing a suboptimal response may benefit from switching to risankizumab with regard to skin symptoms, quality of life symptoms and psoriasis symptoms. …

Hosp Univ Fundacion Alcorcon /ID# 214033
 (4.2 away) Contact site
  • 16 Jun, 2021
  • +74 other locations
6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome

Background: Systemic corticosteroids are considered in patients with an adverse clinical course suffering from conditions like the acute respiratory distress syndrome (ARDS) and septic shock. Treated patients not only show improved respiratory function, but also hemodynamic status and overall multiple organ dysfunction score. Objective: To evaluate the safety and effectiveness …

organ dysfunction syndrome
Francisco Ortu o Anderiz
 (8.2 away) Contact site
  • 07 Nov, 2020
  • +3 other locations
Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients

To compare the sustained virological response (SVR = ribonucleic acid (RNA) - hepatitis C virus (HCV) undetectable at week 24 before end the treatment) in chronic hepatitis C patients genotype 1-4 co-infected with HIV-HCV, treated with Peginterferón alfa-2a (40 KD) 180 µg/week and Ribavirin (2000 mg/day during 4 weeks, follow …

ribonucleic acid
blood pregnancy test
HIV Infection
Hospital de Alcorcon
 (4.2 away) Contact site
  • 07 Nov, 2020
  • +37 other locations
Chemotherapy and Imatinib in Young Adults With Acute Lymphoblastic Leukemia Ph (BCR-ABL) POSITIVE

20-25% of patients over 15 years with acute lymphoblastic leukemia (ALL) have the Philadelphia chromosome or BCR-ABL rearrangement. Traditionally, intensive chemotherapy followed by hematopoietic stem cell transplantation (HSCT) have formed the basis allogeneic treatment of this disease, but the results have been poor (60-75% complete remissions-RC-and probability of long-term survival …

Hospital de Alcorc n
 (4.2 away) Contact site
  • 03 Feb, 2021
  • +111 other locations
Preoperative Preparation With Lugol Solution in Patients With Graves-Basedow Disease.

Currently, both the American Thyroid Association and the European Thyroid Association recommend the use of Lugol Solution (LS) in the preparation of patients undergoing thyroidectomy for Graves' disease (GD), but their recommendations are based on a low level of evidence. This means that its use is not generalized among the …

body mass index
antibiotic prophylaxis
Hospital Universitario Puerta de Hierro
 (4.7 away) Contact site
  • 27 Jan, 2021
  • +20 other locations
Efficacy of Cloxacillin and Fosfomycin Combination Versus Cloxacillin Monotherapy in Patients With MSSA Bacteremia

Background: Despite management improvement in lasts years, S.aureus bacteremia leads to high morbidity and mortality. For over 50 years, methicillin-susceptible S.aureus (MSSA) bacteremia standard treatment was cloxacillin. Previous studies using different therapies and combination treatment fall to improve survival in these patients. Aim: to demonstrate the efficacy of the cloxacillin …

Hospital Universitario Ram n y Cajal
 (9.7 away) Contact site
  • 21 Mar, 2021
  • +13 other locations
Short-course Antibiotic Treatment in Gram-positive Cocci Infective Endocarditis

Background: it is well known that most serious complications of infective endocarditis (IE) appear in the so-called "critical phase" of the disease, which are the first days after diagnosis. Subsequently, the vast majority of patients who overcome this acute phase has a favourable evolution, and usually stay in the hospital …

Cardiovascular Institute. Hospital Cl nico San Carlos
 (8.2 away) Contact site
  • 18 Feb, 2021
  • 1 location
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

This study aims to determine if treatment with apixaban, compared with aspirin, will reduce the risk of ischemic stroke and systemic embolism in patients with device-detected sub-clinical atrial fibrillation and additional risk factors for stroke.

vascular disease
atrial fibrillation
ischemic stroke
Hospital Puerta de Hierro Majadahonda
 (4.7 away) Contact site
  • 26 Jan, 2021
  • +131 other locations
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver fibrosis and eventual cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is …

obeticholic acid
liver disease
glutaric acid
Hospital Universitario Puerta De Hierro Majadahonda
 (4.7 away) Contact site
  • 27 May, 2021
  • +322 other locations