Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Cape Town, South Africa Clinical Trials

A listing of Cape Town, South Africa clinical trials actively recruiting patients volunteers.

RESULTS

Found (102) clinical trials

Sternal Closure With SternaLock 360: First in Man Study

The purpose of this study is to evaluate a new technology for sternal closure that combines rigid plate fixation with a cerclage material in patients undergoing a cardiac surgery subsequent to a full median sternotomy. This study will evaluate intraoperative outcomes related to the surgical technique and performance of the ...

Phase

0.0 miles

Learn More »

Observation of Benefits for Patients Implanted With a Hearing Implant of the Company Cochlear

The clinical investigation is designed as a prospective repeated measures longitudinal study with intra-subject controls, using a selection of subjective evaluation tools to assess patient related benefits from hearing implant treatment of permanent hearing loss. Clinically standard self-assessment scales, threshold measures and a general hearing history profile questionnaires for the ...

Phase N/A

0.0 miles

Learn More »

Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected Children and Adolescents Virologically Suppressed on a 2-NRTI-Containing Regimen

Cohorts 2, 3, and 4 will be on a boosted protease inhibitor (PI) or any other 3rd ARV agent and will switch their current 2-NRTI-containing regimen to open-label F/TAF while continuing their boosted PI or 3rd agent through 48 weeks. A minimum of 10 participants each in Groups 1 and ...

Phase

0.0 miles

Learn More »

Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF

The primary hypothesis in this trial is that the treatment with vericiguat 10 mg or 15 mg in patients with HFpEF improves the KCCQ PLS (Kansas City Cardiomyopathy Questionnaire Physical limitation score) compared to placebo after 24 weeks of treatment.

Phase

0.0 miles

Learn More »

Ureteral Stenting After Ureteroscopy for Stone Treatment A Global Perspective on Indications and Outcomes

BACKGROUND AND RATIONALE The majority of patients with stones receive an indication for its active removal by ureteroscopy. In the last two decades, endourological treatment techniques have evolved with several technological advances through miniaturisation of ureteroscopes, digital improvements, and optical imaging enhancement techniques leading to a better image quality, and ...

Phase N/A

0.0 miles

Learn More »

HIV in Orthopaedic Skeletal Trauma Study

Primary research question Does Human Immunodeficiency Virus (HIV) alter the fracture repair process? Aim To establish whether HIV is a risk factor for the development of delayed bone union or nonunion following a fracture. Study Setting Orthopaedic and Trauma Department, Groote Schuur Hospital (GSH), Cape Town, South Africa. Study design ...

Phase N/A

0.0 miles

Learn More »

Feasibility of Centralized Therapeutic Drug Monitoring of Fluoroquinolones in Multi-Drug Resistant Tuberculosis Patients

Observational, multi-centre, prospective study to investigate the feasibility of centralized TDM of moxifloxacin and levofloxacin in MDR-TB patients by determining turn-around time between sampling and receiving dosing advice. In addition, the effect of TDM will be evaluated by comparing treatment results of prospective patients receiving TDM with historical controls without ...

Phase N/A

0.0 miles

Learn More »

Zone 2 Flexor Tendon Repair With CoNextions TR Implant System

Prospective, randomised, controlled trial of a novel implant intended for use during surgical repair of lacerated Zone 2 flexor digitorum profundus tendons.

Phase

0.0 miles

Learn More »

Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa

Clinical Clinical depression is one of the highest comorbidities to HIV/AIDS, with estimated rates up to 34.9 percent. Depression, in the context of HIV, leads to poor self-care behavior such as non-adherence to ART and worse retention in care, which are critical for treatment success. Based on our prior work, ...

Phase N/A

0.0 miles

Learn More »

Rapid Diagnosis of Pulmonary Tuberculosis

Early case detection, treatment, and prompt household contact investigation, depend on rapid microbiological confirmation, by direct smear microscopy of acid-fast bacilli, in patients with suspected pulmonary tuberculosis. Since delayed diagnosis may result in death due to lack of appropriate therapy, rapid microbiological diagnosis is especially critical in HIV-infected persons. Improved ...

Phase N/A

0.0 miles

Learn More »