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Bellville, Cape Town, South Africa Clinical Trials

A listing of Bellville, Cape Town, South Africa clinical trials actively recruiting patients volunteers.

RESULTS

Found (5) clinical trials

Evaluating the Pharmacokinetics Safety and Tolerability of Bedaquiline in HIV-Infected and HIV-Uninfected Infants Children and Adolescents With Multidrug-Resistant Tuberculosis

This purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability of bedaquiline (BDQ) in combination with an optimized background multidrug-resistant tuberculosis (MDR-TB) treatment regimen in HIV-infected and HIV-uninfected infants, children, and adolescents. The study will enroll HIV-infected and HIV-uninfected children 0 to 18 years of age ...

Phase

1.34 miles

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Evaluating the Safety Tolerance and Pharmacokinetics of a Raltegravir-Containing Antiretroviral Therapy (ART) Regimen in Infants and Children Infected With HIV and TB

People who are infected with HIV are also at risk for becoming infected with TB, particularly in many resource-limited settings, including Sub-Saharan Africa. Rifampicin is a medication commonly used to treat TB. There is a need for HIV treatment regimens that contain newer ARV medications that are well-tolerated and have ...

Phase

1.34 miles

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Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission

The purpose of this study is to explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants. The study will enroll two cohorts. Cohort 1 will include infants at high risk for in utero ...

Phase

1.35 miles

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Safety of and Immune Response to Dolutegravir in HIV-1 Infected Infants Children and Adolescents

DTG is an HIV medicine in the integrase inhibitor drug class. The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of DTG in HIV-1 infected infants, children, and adolescents. Participation in this study will last approximately 48 weeks, followed by long-term safety follow-up that ...

Phase

1.54 miles

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Contingency Management for Meth in South Africa Methamphetamine Abuse in South Africa

This study will correlate MA-abstinence outcomes from an 8-week program of voucher-based incentives using an escalating schedule for 30 treatment-seeking, MA-dependent individuals with scores on tasks of working memory and assessments of neuropsychological and demographic status. At the beginning and end of the CM program, participants will participate in MRI ...

Phase

9.62 miles

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