Tula, Russian Federation Clinical Trials

A listing of Tula, Russian Federation clinical trials actively recruiting patients volunteers.

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Found 26 clinical trials
Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2015 (ALL-MB 2015)

QUESTIONS AND OBJECTIVES OF ALL-MB 2015 STUDY Will the new risk group stratification (especially of T-ALL) to improve overall and event-free survival? Will the new protocol is effective and feasible in patients older than 15 years, and especially in young adults? Whether the intermittent dexamethasone administration in induction will result …

adult t-cell leukemia/lymphoma
b-cell acute lymphoblastic leukemia
lymphoid leukemia
daunorubicin
dexamethasone
N. Dmitrieva Ryazan Regional Clinical Children's Hospital
 (88.4 away) Contact site
  • 161 views
  • 23 Jan, 2021
  • +58 other locations
Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to explore the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active Crohn's Disease.

crohn's disease
corticosteroids
immunomodulators
endoscopy
ileal disease
Tula Regional Clinical Hospital
 (3.4 away) Contact site
  • 865 views
  • 09 Mar, 2021
  • +420 other locations
Efficacy and Safety Study of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in ESA Na ve Subjects Who Require Red Blood Cell Transfusions

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept (ACE-536) …

bone marrow procedure
anemia
erythropoietin
cancer
blood transfusion
Tula Regional Oncology Center
 (3.4 away) Contact site
  • 289 views
  • 01 Aug, 2021
  • +258 other locations
A Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma

A study designed to evaluate the safety and efficacy of venetoclax plus dexamethasone (VenDex) compared with pomalidomide plus dexamethasone (PomDex) in participants with t(11;14)-positive Relapsed or Refractory Multiple Myeloma.

pomalidomide
lenalidomide
measurable disease
proteasome inhibitor
refractory multiple myeloma
Tula Regional Clinical Hospital /ID# 223226
 (3.4 away) Contact site
  • 91 views
  • 06 Jul, 2021
  • +268 other locations
Phase II Study to Assess AFM13 in Patients With R/R CD30-positive T-cell Lymphoma or Transformed Mycosis Fungoides

This is a phase II study to evaluate the antitumor activity and safety of AFM13 given as monotherapy in patients with CD30-positive T-cell lymphoma. The investigational medicinal product AFM13 is a tetravalent bispecific chimeric (anti-human CD30 x anti-human CD16A) recombinant antibody construct which is being developed to treat CD30-positive malignancies. …

brentuximab vedotin
measurable disease
mycosis fungoides
t-cell lymphoma
fungal infection
Saratov State Medical University
 (389.9 away) Contact site
  • 32 views
  • 30 Jul, 2021
  • +83 other locations
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is a Phase 3, open-label, multicenter extension study to evaluate safety and efficacy of ozanimod in subjects with moderately to severely active Crohn's Disease.

crohn's disease
remission
Tula Regional Clinical Hospital
 (3.4 away) Contact site
  • 1035 views
  • 22 Feb, 2021
  • +807 other locations
A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to demonstrate the effect of oral ozanimod as maintenance therapy in subjects with moderately to severely active Crohn's Disease.

crohn's disease
abdominal pain
remission
Tula Regional Clinical Hospital
 (3.4 away) Contact site
  • 858 views
  • 23 Feb, 2021
  • +780 other locations
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199) With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL

The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.

bendamustine
venetoclax
obinutuzumab
rituximab
cyclophosphamide
Research Site
 (3.4 away) Contact site
  • 342 views
  • 31 May, 2021
  • +243 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

myocardial infarction
arterial disease
acute coronary syndrome
diabetes
stemi
6430043 - Tula Regional Clinical Hospital
 (3.4 away) Contact site
  • 1118 views
  • 01 Aug, 2021
  • +3430 other locations
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis

The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.

eczema
corticosteroids
topical agents
ly3009104
topical corticosteroid
State Healthcare Instit Tula Reg Dermatov Dispensary
 (3.4 away) Contact site
  • 103 views
  • 31 Jul, 2021
  • +189 other locations