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Montreal, Quebec Clinical Trials

A listing of Montreal, Quebec clinical trials actively recruiting patients volunteers.

RESULTS

Found (49) clinical trials

Effect of Ketamine on Analgesia Post-Cardiac Surgery

This is a randomized, controlled, double-blind pilot study to determine the effectiveness of intraoperative Ketamine administration on pain after coronary artery bypass surgery. Patients will be randomized to receive ketamine or saline prior to incision, with a continuous infusion throughout surgery. Opioid dose administered in the first 48 hours will ...

Phase

3.02 miles

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Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy

Data from a previous single arm study (RESPITE) indicate that transition from PDE5i to riociguat may be feasible, safe and beneficial in patients not adequately responding to PDE5i. REPLACE is a randomized controlled study to confirm the potential clinical benefit of transition from PDE5i to riociguat. Satisfactory clinical response in ...

Phase

3.02 miles

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Fesoterodine on Urgency Episodes in Parkinson's Disease Population

Study purpose and rationale: Patients with Parkinson's disease (PD) commonly develop lower urinary tract symptoms as their disease severity progresses. The most frequent symptoms are nocturia (night time urinary frequency), urinary frequency and urgency. (1) The effects on voiding function of levodopa and dopamine agonists for the treatment of motor ...

Phase

3.02 miles

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Effect of Vitamin D3 Supplementation on Arterial and Bone Remodeling in Chronic Kidney Disease Patients

Structural changes to large arteries and abnormalities in mineral and bone metabolism are frequent manifestations in patients with chronic kidney disease (CKD). Together, they contribute in a large part to the heightened morbidity and mortality observed in this population. Epidemiological data in end stage renal disease and in the general ...

Phase

3.02 miles

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Efficacy and Safety of Poly-L-lactic Acid

This is a phase IV prospective, multicentre, single cohort, open-label clinical trial evaluating the efficacy and safety of Poly-L-lactic acid (Sculptra Aesthetic) for the treatment of contour deformities of the buttocks region

Phase

3.67 miles

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An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers

A study to evaluate the safety of Nivolumab given in combination with Ipilimumab in patients with advanced cancers. The initial group will enroll patients with newly diagnosed Stage 4 or non-small cell lung cancer that has come back.

Phase

3.9 miles

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The Canadian Prevention of Renal and Cardiovascular Endpoints Trial

The pilot study is designed in two phases. The first phase is intended to provide data on some key points that need to be addressed prior to future funding applications to the CIHR and the NHLBI. These applications are currently tentatively planned for the fall of 2005. The second phase ...

Phase

3.9 miles

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PENTHROX in the Canadian Emergency Department (ED)

The study will assess the change in pain intensity over 20 minutes from start of administration of PENTHROX and will generate Real World Evidence in support of existing clinical trial data including effectiveness, safety and additional parameters of low dose MEOF (PENTHROX) in Canadian EDs.

Phase

3.9 miles

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Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient

Temporomandibular disorders (TMD) is an umbrella term to describe different disorders that affect the temporomandibular joint (TMJ) and/or muscles of mastication 1. TMD is one of the most common chronic orofacial pain conditions and the second most commonly occurring musculoskeletal condition, affecting 5-12% of the U.S and Canada. As other ...

Phase

3.91 miles

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Mindfulness-Based Cognitive Therapy for Depression and Anxiety

About 10-20% of older patients in primary care suffer from symptoms of depression and/or anxiety. Depression and anxiety are associated with higher rates of cognitive decline, lower quality of life, increased medical comorbidity, and higher mortality rates in these patients. Given the world's aging population and consequent rapid increase in ...

Phase

3.98 miles

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