Rio Piedras, Puerto Rico Clinical Trials

A listing of Rio Piedras, Puerto Rico clinical trials actively recruiting patients volunteers.

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Found 91 clinical trials
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with chemoradiotherapy (CRT) versus CRT alone in participants with muscle-invasive bladder cancer (MIBC). The primary hypothesis is that pembrolizumab + chemoradiotherapy is superior to placebo + chemoradiotherapy with respect to bladder intact event-free survival.

pembrolizumab
invasive bladder cancer
metastatic bladder carcinoma
gemcitabine
mitomycin
PAN American Center Oncologic ( Site 0280)
 (1.1 away) Contact site
  • 76 views
  • 12 Jun, 2021
  • +104 other locations
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome (MDS) is a group of disorders that gradually affect the ability of a person's bone marrow (semi-liquid tissue present in many bones like backbones) to produce normal blood cells. Some people with MDS have a risk of the disease progressing to acute myeloid leukemia (AML), and a risk …

azacitidine
remission
leukemia
anemia
myeloid leukemia
VA Caribbean Healthcare System /ID# 221012
 (2.5 away) Contact site
  • 27 views
  • 09 Jun, 2021
  • +266 other locations
Amcenestrant (SAR439859) Plus Palbociclib as First Line Therapy for Patients With ER (+) HER2(-) Advanced Breast Cancer

Primary Objective: To determine whether Amcenestrant (SAR439859) in combination with palbociclib improvesprogression free survival (PFS) when compared with letrozole in combination with palbociclib in participants with ER+, HER2- advanced breast cancer who have not received any prior systemic anticancer therapies for advanced disease. Secondary Objective: To compare the overall survival …

advanced breast cancer
erbb2
HER2
letrozole
palbociclib
Investigational Site Number 8400003
 (2.3 away) Contact site
  • 0 views
  • 09 Jun, 2021
  • +123 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
hemoglobin a1c
body mass index
GCM Medical Group PSC
 (2.3 away) Contact site
  • 593 views
  • 31 May, 2021
  • +872 other locations
Study of Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations

This is a Phase 3 multicenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy of giving an oral targeted FGFR1-3 inhibitor, infigratinib, as adjuvant treatment following surgery in adult subjects with invasive urothelial carcinoma and susceptible FGFR3 genetic alterations (mutations, and gene fusions or translocations [ie, rearrangements) who have disease …

Centro M dico de Puerto Rico
 (4.4 away) Contact site
  • 1 views
  • 10 May, 2021
  • +102 other locations
Long-Term Study That Measures the Safety and Efficacy of BMS-986165 in Participants With Psoriasis.

The main purpose of this study is to characterize the long-term safety and efficacy of the drug BMS-986165 in patients who have been previously enrolled in an applicable Phase 3 psoriasis study.

bms-986165
Local Institution
 (2.3 away) Contact site
  • 365 views
  • 26 Jan, 2021
  • +338 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

tremelimumab
atezolizumab
sunitinib
pd-l1
nephrectomy
Pan American Center for Oncology Trials LLC
 (6.8 away) Contact site
  • 157 views
  • 12 Jun, 2021
  • +672 other locations
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to demonstrate the non-inferiority of the vaccine seroresponse to meningococcal serogroups A, C, Y, and W following administration of 2 doses of MenACYW conjugate vaccine compared to 2 doses of MENVEO when given concomitantly with routine pediatric vaccines to infants and toddlers 6 …

Investigational Site Number 6300014
 (4.3 away) Contact site
  • 420 views
  • 12 Jun, 2021
  • +57 other locations
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program

This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program. The study will last about 2 years (29 visits).

dyslipidemia
cardiovascular disease
body mass index
hypertension
Advanced Clinical Research, LLC
 (8.8 away) Contact site
  • 0 views
  • 28 May, 2021
  • +74 other locations
A Research Study to Compare Two Types of Insulin a New Insulin Insulin Icodec and an Available Insulin Insulin Degludec in People With Type 2 Diabetes Who Have Not Used Insulin Before (ONWARDS 3)

This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin …

Novo Nordisk Investigational Site
 (8.8 away) Contact site
  • 0 views
  • 04 Jun, 2021
  • +81 other locations