Rio Piedras, Puerto Rico Clinical Trials

A listing of Rio Piedras, Puerto Rico clinical trials actively recruiting patients volunteers.

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Found 91 clinical trials
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS)

MRI
interferon
fingolimod
Novartis Investigative Site
 (4.1 away) Contact site
  • 72 views
  • 22 May, 2021
  • +99 other locations
Topical or Ablative Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Squamous Intraepithelial Lesions

This randomized phase III trial compares topical or ablative treatment with active monitoring in preventing anal cancer in patients with human immunodeficiency virus (HIV) and high-grade squamous intraepithelial lesions (HSIL). Anal HSIL is tissue in the anal canal that has been damaged by infection with human papillomavirus (HPV) and is …

fluorouracil
HIV Vaccine
infrared photocoagulation therapy
immunodeficiency
hsil
University of Puerto Rico
 (6.8 away) Contact site
  • 143 views
  • 24 Jan, 2021
  • +24 other locations
INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections

Stage A: To evaluate the safety and efficacy of red blood cells (RBCs) prepared with the INTERCEPT Blood System for Red Blood Cells Pathogen Reduction Treatment (PRT) in comparison to conventional RBCs in patients who require RBC transfusion support. Stage B: To provide early access to the INTERCEPT pathogen reduction …

sepsis
blood transfusion
Banco de Sangre de Servicios Mutuos, Inc. (BSSM)
 (5.5 away) Contact site
  • 196 views
  • 10 Apr, 2021
  • +10 other locations
Phase 3 Study of ProstAtak Immunotherapy With Standard Radiation Therapy for Localized Prostate Cancer

The purpose of this study is to evaluate the effectiveness of ProstAtak immunotherapy in combination with radiation therapy for patients with intermediate-high risk localized prostate cancer. ProstAtak kills tumor cells and stimulates a cancer vaccine effect. Killing tumor cells in an immune stimulatory environment induces the body's immune system to …

cancer vaccine
androgen suppression
antiandrogen therapy
external beam radiation therapy
tumor cells
VA Caribbean Healthcare System
 (3.3 away) Contact site
  • 1420 views
  • 02 Jun, 2021
  • +78 other locations
A Study of the Efficacy and Safety of Upadacitnib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Conventional and/or Biologic Therapies

The objective of this study is to evaluate the efficacy and safety of upadacitinib compared to placebo as induction therapy in participants with moderately and severely active Crohn's disease (CD).

abdominal pain
conventional treatment
crohn's disease
endoscopy
mucosal inflammation
Mindful Medical Research /ID# 203358
 (2.6 away) Contact site
  • 824 views
  • 02 Jun, 2021
  • +730 other locations
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis

A double-blind placebo controlled randomized Phase 3 study to determine if 80 or 100 mg of MGL-3196 as compared with placebo resolves NASH on liver biopsy and prevents progression to cirrhosis and/or advanced liver disease

fibroscan
liver disease
mri-pdff
ballooning degeneration
steatosis
Fundaci n De Investigaci n De Diego
 (6.8 away) Contact site
  • 167 views
  • 12 Mar, 2021
  • +219 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

calcium
step 2
neutrophil count
pembrolizumab
metastatic renal cell carcinoma
Pan American Center for Oncology Trials LLC
 (6.8 away) Contact site
  • 157 views
  • 16 Jun, 2021
  • +672 other locations
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer

The purpose of this study is to evaluate the effectiveness of niraparib in combination with abiraterone acetate plus prednisone (AAP) compared to AAP plus placebo.

VA Caribbean Healthcare System
 (3.3 away) Contact site
  • 498 views
  • 26 Jan, 2021
  • +480 other locations
A Phase 3 Study to Evaluate the Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease (NAFLD) Patients

A double-blind placebo controlled randomized Phase 3 study to evaluate the safety and tolerability of once-daily, oral administration of 80 or 100 mg resmetirom versus matching placebo. 100 patients will be enrolled in a 100 mg open-label arm.

fibroscan
dyslipidemia
liver disease
mri-pdff
fatty liver
Fundacion de Investigacion de Diego
 (6.8 away) Contact site
  • 237 views
  • 24 Jan, 2021
  • +67 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
florbetapir
alzheimer's disease
flortaucipir
mini-mental state examination
INSPIRA Clinical Research
 (2.6 away) Contact site
  • 79 views
  • 13 Jun, 2021
  • +382 other locations