Rio Piedras, Puerto Rico Clinical Trials

A listing of Rio Piedras, Puerto Rico clinical trials actively recruiting patients volunteers.

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Found 224 clinical trials
A Study to Evaluate the Pharmacokinetics Safety and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis

This is a study to evaluate pharmacokinetics, safety and tolerability of upadacitinib in pediatric participants with polyarticular course juvenile idiopathic arthritis. This study consists of two parts: Part 1 is multiple-cohort study that consists of two sequential multiple-ascending dose groups. Participants benefiting from the study drug with no ongoing adverse …

swelling
methotrexate
arthritis
GCM Medical Group PSC - Hato Rey /ID# 211702
 (2.3 away) Contact site
  • 95 views
  • 26 Jan, 2021
  • +30 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

testosterone topical
testosterone
serum testosterone
replacement therapy
testosterone level
GCM Medical Group, PSC /ID# 170466
 (2.3 away) Contact site
  • 16823 views
  • 18 Jun, 2021
  • +471 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

metastatic renal cell carcinoma
measurable disease
cancer
cabozantinib
neutrophil count
Pan American Center for Oncology Trials LLC
 (6.8 away) Contact site
  • 157 views
  • 16 Jun, 2021
  • +672 other locations
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer

The purpose of this study is to evaluate the effectiveness of niraparib in combination with abiraterone acetate plus prednisone (AAP) compared to AAP plus placebo.

VA Caribbean Healthcare System
 (3.3 away) Contact site
  • 498 views
  • 26 Jan, 2021
  • +480 other locations
Osimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib

This study (the SAVANNAH study) will investigate the efficacy of osimertinib in combination with savolitinib in patients with EGFRm+ and MET+, locally advanced or metastatic NSCLC who have progressed following treatment with osimertinib

EGFR
line of therapy
cancer
metastatic non-small cell lung cancer
renal function
Research Site
 (2.3 away) Contact site
  • 109 views
  • 03 Jun, 2021
  • +141 other locations
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

ileocolitis
crohn's disease
endoscopy
colitis
abdominal pain
VA Caribbean Healthcare System - San Juan VA Medical Center
 (2.5 away) Contact site
  • 792 views
  • 18 Jun, 2021
  • +796 other locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
VA Caribbean Healthcare System /ID# 221245
 (2.5 away) Contact site
  • 604 views
  • 16 Jun, 2021
  • +772 other locations
A Safety and Efficacy Study of Oral Venetoclax Tablets and Injectable Azacitidine Versus Best Supportive Care as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy to Evaluate Improvement in Relapse-Free Survival

The main objective of this study is to evaluate safety and efficacy of venetoclax in combination with azacitidine (AZA) and best supportive care (BSC) compared to BSC as maintenance therapy in adult participants with acute myeloid leukemia (AML) in first remission after conventional chemotherapy. This study will be conducted in …

venetoclax
remission
consolidation chemotherapies
cancer
azacitidine
Pan American Center for Oncology Trials, LLC /ID# 214953
 (4.4 away) Contact site
  • 40 views
  • 09 Jun, 2021
  • +255 other locations
Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)

A multi-center evaluation of aldafermin in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis.

mri-pdff
fibrosis
cirrhosis
NGM Clinical Study Site
 (1.8 away) Contact site
  • 104 views
  • 08 Apr, 2021
  • +64 other locations
A Study to Evaluate the Safety Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1

This study will be conducted in two stages and will test the safety/tolerability, pharmacokinetics (how the body handles study drug) and pharmacodynamics (effects on the immune system and the virus) of the study drug ABBV-181 in Human immunodeficiency virus (HIV)-1 infected participants undergoing Antiretroviral therapy (ART) interruption.

hiv-1 rna measurement
HIV Vaccine
immunodeficiency
antiretroviral agents
drug test
Puerto Rico AIDS Clinical Trials Unit CRS /ID# 213761
 (4.4 away) Contact site
  • 147 views
  • 16 Jun, 2021
  • +33 other locations