Rio Piedras, Puerto Rico Clinical Trials

A listing of Rio Piedras, Puerto Rico clinical trials actively recruiting patients volunteers.

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Found 12 clinical trials
REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

HPV-303 is a prospective, randomized, double-blind, placebo-controlled phase 3 study of VGX-3100 delivered intramuscularly (IM) followed by electroporation (EP) delivered with CELLECTRA 5PSP in adult women with histologically confirmed high-grade squamous intraepithelial lesions (HSIL) (cervical intraepithelial neoplasia grade 2 [CIN2] or grade 3 [CIN3]) of the cervix, associated with HPV-16 …

hpv types
hsil
vgx-3100
cervical intraepithelial neoplasia
cin 3
Puerto Rico Translational Research Center (PRTRC)
 (4.4 away) Contact site
  • 498 views
  • 11 Jun, 2021
  • +79 other locations
Pharmacokinetic Safety and Efficacy of B/F/TAF in HIV-1 Infected Virologically Suppressed Pregnant Women in Their Second and Third Trimesters

The primary objective of this study is to evaluate the steady state pharmacokinetics of bictegravir (BIC) and confirm the dose of BIC/emtricitabine/tenofovir alafenamide (B/F/TAF) 50/200/25 mg fixed dose combination (FDC) in HIV-1 infected, virologically suppressed pregnant women in their second and third trimesters.

Maternal Infant Studies Center (CEMI)
 (2.3 away) Contact site
  • 60 views
  • 12 Jun, 2021
  • +18 other locations
Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making

This trial studies how well a breast cancer surgery decision aid works in increasing patient engagement in decision making for patients with newly diagnosed stage 0-III breast cancer. The trial also examines barriers to patient engagement even with the use of a decision aid, and if barriers are more likely …

hearing impairment
breast surgery
Pan American Center for Oncology Trials LLC
 (6.8 away) Contact site
  • 17 views
  • 16 Jun, 2021
  • +63 other locations
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD

The Ischemia-IMT (Ischemia-Intensive Medical Treatment Reduces Events in Women with Non-Obstructive CAD), subtitle: Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR) trial is a multicenter, prospective, randomized, blinded outcome evaluation (PROBE design) evaluating intensive statin/ACE-I (or ARB)/aspirin treatment (IMT) vs. usual care (UC) in 4,422 symptomatic women patients …

hmg-coa reductase inhibitors
aspirin
rosuvastatin
angina pectoris
stroke
VA Caribbean Healthcare System
 (3.3 away) Contact site
  • 492 views
  • 03 Feb, 2021
  • +70 other locations
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and mental health. This study will evaluate how well elagolix in combination with combined oral contraceptives (COC) works within the body and/or how safe it …

dysmenorrhea
combined oral contraceptives
endometriosis
elagolix
Rodriguez-Ginorio, San Juan /ID# 217233
 (2.3 away) Contact site
  • 392 views
  • 20 Jun, 2021
  • +195 other locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

paclitaxel
serum pregnancy test
carcinoma
absolute neutrophil count
MRI
Centro Comprensivo de Cancer de UPR
 (1.8 away) Contact site
  • 71 views
  • 20 Jun, 2021
  • +172 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

primary peritoneal carcinoma
paclitaxel
carcinoma
liver metastasis
absolute neutrophil count
Centro Comprensivo de Cancer de UPR
 (1.8 away) Contact site
  • 1729 views
  • 20 Jun, 2021
  • +211 other locations
Effect of Low vs Moderate-intensity Endurance Exercise on Physical Functioning Among Breast Cancer Survivors

The purpose of this study is to evaluate the effect of two exercise programs: 1) one program will be at low intensity; 2) the other program will be at moderate intensity. One hundred forty two women who are breast cancer survivors will be recruited. Participants will be educated on a …

breast cancer
breast cancer staging
cancer
immunostimulant
Puerto Rico Clinical and Translational Research Consortium
 (6.8 away) Contact site
  • 4 views
  • 15 May, 2021
  • 1 location
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

This phase III trial compares whether the addition of pembrolizumab to radiation therapy is more effective than radiation therapy alone in reducing the risk of cancer coming back (recurrence) in patients with newly diagnosed stage I-II endometrial cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

Centro Comprensivo de Cancer de UPR
 (1.8 away) Contact site
  • 1 views
  • 17 Jun, 2021
  • +127 other locations
A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)

The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth and fifth years of use when used as the only method of contraception. The ENG implant is currently approved for a 3-year duration, and this study aims to …

nexplanon
contraceptive use
etonogestrel
regular menstrual cycles
implant removal
Fundacion de Investigacion de Diego ( Site 0305)
 (1.8 away) Contact site
  • 0 views
  • 20 Jun, 2021
  • +62 other locations