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Vila Nova De Famalicão, Portugal

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  • The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

    Phase

    2

    Span

    135 weeks

    Sponsor

    Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

    Juiz de Fora

    Recruiting

  • A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

    Phase

    3

    Span

    303 weeks

    Sponsor

    Biogen

    Juiz de Fora, Minas Gerais

    Recruiting

  • A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis

    Phase

    3

    Span

    643 weeks

    Sponsor

    Eli Lilly and Company

    Juiz de Fora, Minas Gerais

    Recruiting

  • A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

    This is a Phase III randomized, double-blind, parallel group, multi-center event-driven study comparing BGF MDI 320/14.4/9.6 μg BID with GFF MDI 14.4/9.6 μg BID in participants with COPD who are at risk of a cardiopulmonary event.

    Phase

    3

    Span

    211 weeks

    Sponsor

    AstraZeneca

    Juiz de Fora

    Recruiting

  • A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease.

    Phase

    3

    Span

    276 weeks

    Sponsor

    AbbVie

    Juiz de Fora, Minas Gerais

    Recruiting

  • A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

    Phase

    2/3

    Span

    200 weeks

    Sponsor

    GlaxoSmithKline

    Juiz de Fora

    Recruiting

  • A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

    Phase

    4

    Span

    260 weeks

    Sponsor

    GlaxoSmithKline

    Juiz de Fora

    Recruiting

  • A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

    Phase

    3

    Span

    222 weeks

    Sponsor

    GlaxoSmithKline

    Juiz de Fora

    Recruiting

  • A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus (AMETHYST)

    Litifilimab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting blood dendritic cell antigen 2 and is being investigated for the potential treatment of systemic lupus erythematosus and cutaneous lupus erythematosus. The primary objectives of the study are to evaluate the efficacy of litifilimab compared with placebo in reducing skin disease activity measured by the CLA-IGA-R score [Parts A and B (US)] and the Cutaneous Lupus Erythematosus Disease Area and Severity Index Activity (CLASI-A) score [Part B (ROW)] in participants with active SCLE and/or CCLE with or without systemic manifestations and refractory and/or intolerant to antimalarials. The secondary objectives of the study are to evaluate the efficacy of litifilimab in reducing SCLE and/or CCLE disease activity by CLA-IGA-R, CLASI-A; to evaluate additional efficacy parameters of litifilimab in reducing SCLE and/or CCLE disease activity; safety; tolerability; and immunogenicity of litifilimab [Parts A and B].

    Phase

    2/3

    Span

    274 weeks

    Sponsor

    Biogen

    Juiz de Fora, Minas Gerais

    Recruiting

  • Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

    Phase

    3

    Span

    214 weeks

    Sponsor

    Alpine Immune Sciences Inc, A Subsidiary of Vertex

    Juiz de Fora

    Recruiting

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