Szcezecin, Poland
Study to Investigate Comparative Efficacy, Safety and Immunogenicity Between AVT16 and Entyvio
The study will consist of a screening period, a treatment and assessment period and an End of Study visit. Eligibility for the study will be determined during a screening period. Subjects who meet the eligibility criteria will be randomised to either AVT16 or Entyvio.
Phase
3Span
101 weeksSponsor
Alvotech Swiss AGSopot
Recruiting
A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)
This is a Phase 2, randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy, safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of rosnilimab in subjects with moderate to severe ulcerative colitis (UC).
Phase
2Span
130 weeksSponsor
AnaptysBio, Inc.Sopot
Recruiting
The Efficacy of AP029 Mix in Patients With Impaired Carbohydrate Metabolism
Randomized, double-blind, cross over study conducted under medical supervision on 1) group of 20 patients with type II diabetes and 2) group of 10 patients with prediabetes. Study design: 2 months of AP029 supplementation, 1 month wash-out, 2 months of placebo intake. Patients will attend 4 visits. On each visit, the following parameters are analyzed: level of glucose, insulin, HbA1c, hsCRP lipid panel (total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), HDL) and inflammatory and oxidative stress markers. In addition, a questionnaire of symptoms associated with metformin intake will be conducted
Phase
N/ASpan
27 weeksSponsor
AronPharma Sp. z o. o.Sopot
Recruiting
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Phase
2Span
182 weeksSponsor
Gilead SciencesSopot
Recruiting
Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction
Phase
2Span
167 weeksSponsor
Akros Pharma Inc.Sopot
Recruiting
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
This study consists of a screening period followed by a placebo-controlled Part 1 phase and then a placebo-controlled Part 2 phase. An open label Part 3 phase is open to subjects who: complete the Part 2, are considered non-responders following the Part 1, or have disease worsening during Part 2.
Phase
3Span
178 weeksSponsor
Reistone Biopharma Company LimitedSopot
Recruiting
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
Phase
2Span
183 weeksSponsor
Boehringer IngelheimSopot
Recruiting
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Phase
3Span
192 weeksSponsor
Janssen Research & Development, LLCSopot
Recruiting
Phase IIa Study Evaluating AZD7798 in Crohn's Disease
Phase
2Span
143 weeksSponsor
AstraZenecaSopot
Recruiting
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Phase
3Span
219 weeksSponsor
Hoffmann-La RocheSopot
Recruiting