Gdynia, Poland Clinical Trials

A listing of Gdynia, Poland clinical trials actively recruiting patients volunteers.

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Found 105 clinical trials
A Phase 2b, Randomised, Double-Blind, Active Controlled, Multi Centre Study to Evaluate the Efficacy, Safety and Tolerability of Oral AZD9977 and Dapagliflozin Treatment in Patients With Heart Failure and Chronic Kidney Disease (MIRACLE)

The purpose of the study is to evaluate the efficacy and safety of AZD9977 in combination with dapagliflozin compared with dapagliflozin alone and to assess the dose-response relationship, dapagliflozin alone and 3 doses of AZD9977 combined with dapagliflozin on urinary albumin to creatinine ratio (UACR). The study will be conducted …

ejection fraction
MRI
type 2 diabetes mellitus
antihypertensive drugs
diabetes
Research Site
 (5.4 away) Contact site
  • 22 views
  • 25 Oct, 2022
  • +114 other locations
A Phase 2 Study to Evaluate the Efficacy and Safety of MK-1026 in Participants With Hematologic Malignancies

The purpose of this study is to evaluate the safety and efficacy of nemtabrutinib (formerly ARQ 531) in participants with hematologic malignancies of chronic lymphocytic leukemia (CLL)/ small lymphocytic lymphoma (SLL), Richter's transformation, marginal zone lymphoma (MZL), mantle cell lymphoma (MCL), follicular lymphoma (FL), and Waldenström's macroglobulinemia (WM).

leukemia
chronic lymphocytic leukemia
kinase inhibitor
mantle cell lymphoma
hepatitis b surface antigen
Szpitale Pomorskie Sp. z o.o. ( Site 1600)
 (2.2 away) Contact site
  • 33 views
  • 28 Oct, 2022
  • +44 other locations
Efficacy, Safety, Tolerability and Quality of Life of Ongoing Individually Optimized Lipid-lowering Therapy With or Without Inclisiran (KJX839) - a Randomized, Placebo-controlled, Double-blind Multicenter Phase IV Study in Participants With Hypercholesterolemia (V-DIFFERENCE)

Study of efficacy, safety, tolerability and quality of life of inclisiran (KJX839) vs placebo, on top of ongoing individually optimized lipid-lowering therapy, in participants with hypercholesterolemia

lipid-lowering therapy
cholesterol measurement
cardiovascular disease
diabetes
hmg-coa reductase inhibitors
Novartis Investigative Site
 (2.9 away) Contact site
  • 0 views
  • 25 Oct, 2022
  • +89 other locations
A 54-Week, Multicenter, Randomized, Double-blind, Placebo Controlled, Parallel-group Phase 2 Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis (Expedition Lead-in) (Expedition)

The present study (D5272C00001/Legacy #3151-201-008) aims to evaluate the efficacy and safety of brazikumab in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.

hysterectomy
aminosalicylates
prednisone
ulceration
endoscopy
Research Site
 (5.4 away) Contact site
  • 392 views
  • 28 Oct, 2022
  • +73 other locations
An Open Label Phase II Randomized Trial of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Monotherapy as a First Line Therapy in Patients With Unresectable Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Which is Positive for Human Papilloma Virus 16 (HPV16+) and Expresses PD-L1 (AHEAD-MERIT) (AHEAD-MERIT)

An open-label, controlled, multi-site, interventional, 2-arm, Phase II trial of BNT113 in combination with pembrolizumab vs pembrolizumab monotherapy as first line treatment in patients with unresectable recurrent or metastatic HPV16+ HNSCC expressing programmed cell death ligand -1 (PD-L1) with combined positive score (CPS) ≥1. This trial has two parts. Part …

Szpitale Pomorskie Sp.zo.o
 (2.2 away) Contact site
  • 108 views
  • 27 Oct, 2022
  • +61 other locations
An Open-label, Multi-center Extension Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Moderate to Severe Crohn's Disease or Moderate to Severe Ulcerative Colitis

The purpose of this study is to evaluate the long-term safety and efficacy of Deucravacitinib in participants who have previously been enrolled in a Deucravacitinib Phase 2 study for moderate to severe Crohn's disease or moderate to severe Ulcerative Colitis.

ulceration
ulcerative colitis
colitis
crohn's disease
Local Institution
 (5.6 away) Contact site
  • 0 views
  • 27 Oct, 2022
  • +21 other locations
A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy (Astefania)

This is a Phase III, two-arm, randomized, double-blind placebo-controlled study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes.

invasive breast cancer
breast carcinoma
taxane
carcinoma
trastuzumab
Uniwersyteckie Centrum Kliniczne; Klinika Onkologii i Radioterapii
 (8.6 away) Contact site
  • 8 views
  • 28 Oct, 2022
  • +259 other locations
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multicenter Proof-of-concept Study Evaluating Efficacy and Safety of Rilzabrutinib in Adult Patients With Moderate-to-severe Atopic Dermatitis Who Are Inadequate Responders or Intolerant to Topical Corticosteroids

This is a parallel, treatment, Phase 2, double-blind, 2-arm, placebo-controlled study with 2 staggered cohorts (2 arms in each cohort) to evaluate the efficacy and safety of rilzabrutinib in adult participants (aged at least 18 years) with moderate-to-severe AD and intolerance or inadequate response to topical corticosteroids (TCS). In parallel …

eczema
corticosteroids
topical agents
topical corticosteroid
Investigational Site Number :6160005
 (9.9 away) Contact site
  • 0 views
  • 29 Oct, 2022
  • +24 other locations
A Phase IIb, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multicenter Dose Ranging Study of a Subcutaneous Anti-OX40L Monoclonal Antibody (KY1005) in Moderate-to-Severe Atopic Dermatitis (STREAM-AD)

This is an interventional, randomized, parallel group, treatment, Phase IIb, double blind, 5-arm study to assess the effect of Anti-OX40L Monoclonal Antibody (KY1005) in adult participants with moderate to severe atopic dermatitis. The estimated duration is 28 days for screening and then up to approximately day 477 (last dose no …

topical agents
Investigative Site Number: 2404
 (0.4 away) Contact site
  • 2 views
  • 28 Oct, 2022
  • +67 other locations
A Long-term Study to Assess the Safety and Efficacy of Lebrikizumab in Patients With Moderate-to-Severe Atopic Dermatitis (ADjoin) (ADjoin)

This 110-week study is designed to assess the long-term safety and efficacy of lebrikizumab for moderate-to-severe atopic dermatitis.

eczema
atopy
hormonal contraception
topical agents
lebrikizumab
Oddzial Dermatologii COPERNICUS
 (8.9 away) Contact site
  • 626 views
  • 28 Oct, 2022
  • +257 other locations