Tauranga, New Zealand Clinical Trials

A listing of Tauranga, New Zealand clinical trials actively recruiting patients volunteers.

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Found 71 clinical trials
A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy (SKYSCRAPER-07)

The purpose of this study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo in participants with unresectable esophageal squamous cell carcinoma (or those who are unable or unwilling to undergo surgery) and whose cancers have not progressed following definitive concurrent chemoradiotherapy (dCRT). Participants will …

carcinoma
cancer
esophageal cancer
esophagus cancer
chemoradiotherapy
Tauranga Hospital, Clinical Trials Unit; BOP Clinical School
 (3.0 away) Contact site
  • 7 views
  • 09 Jul, 2022
  • +182 other locations
Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection

This is a Phase 1 study in which healthy volunteers and participants with chronic HBV infection will receive VIR-3434 or placebo and will be assessed for safety, tolerability, pharmacokinetics (PK), and antiviral activity (only in participants with chronic HBV infection).

antiviral drugs
hepatitis
chronic hepatitis
Accepts healthy volunteers
Investigative Site
 (2.5 away) Contact site
  • 571 views
  • 26 May, 2022
  • +16 other locations
Study Comparing Investigational Drug HBI-8000 Combined With Nivolumab vs. Nivolumab in Patients With Advanced Melanoma

This is a phase 3 study to compare the efficacy and safety of HBI-8000 or Placebo combined with nivolumab on patients with unresectable or metastatic melanoma and eligible patients who are not adolescents or patients with new, progressive brain metastasis will be stratified by PD-L1 expression and LDH level.

Tauranga Hospital
 (3.2 away) Contact site
  • 10 views
  • 01 Jul, 2022
  • +41 other locations
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy (Astefania)

This is a Phase III, two-arm, randomized, double-blind placebo-controlled study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes.

taxane
invasive breast cancer
growth factor
EGFR
epidermal growth factor
Tauranga Hospital, Clinical Trials Unit; BOP Clinical School
 (3.0 away) Contact site
  • 8 views
  • 15 Jul, 2022
  • +256 other locations
Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma (DREAMM 8)

This study will evaluate the efficacy and safety of belantamab mafodotin in combination with pomalidomide and dexamethasone (Arm A) compared with that of combination of pomalidomide, bortezomib and dexamethasone (Arm B) in participants with relapsed/refractory multiple myeloma (RRMM).

lenalidomide
pomalidomide
refractory multiple myeloma
dexamethasone
bortezomib
GSK Investigational Site
 (0.0 away) Contact site
  • 19 views
  • 21 Jul, 2022
  • +117 other locations
A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)

The purpose of this study is to investigate the effects of nivolumab when given under the skin with or without rHuPH20. This study will include participants with 1 of the following advanced or metastatic tumors approved for treatment with nivolumab monotherapy: non-small cell lung cancer (NSCLC) renal cell carcinoma (RCC) …

carcinoma
solid tumor
primary cancer
Local Institution - 0015
 (3.0 away) Contact site
  • 101 views
  • 23 Jul, 2022
  • +15 other locations
A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years

The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placebo in the prevention of the first invasive extraintestinal pathogenic Escherichia coli disease (IED) event caused by ExPEC9V O-serotypes.

Accepts healthy volunteers
P3 Research Ltd
 (1.1 away) Contact site
  • 142 views
  • 23 Jul, 2022
  • +124 other locations
A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older (EVERGREEN)

The study will enroll up to 27,500 participants in order to demonstrate the efficacy of the active Ad26.RSV.preF-based study vaccine in the prevention of Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed Respiratory Syncytial Virus (RSV)-mediated Lower Respiratory Tract Disease (LRTD) when compared to placebo in adults aged 60 years and …

Accepts healthy volunteers
P3 Research Ltd
 (1.1 away) Contact site
  • 46 views
  • 23 Jul, 2022
  • +249 other locations
A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC) (SKYSCRAPER-03)

The purpose of this study is to evaluate the efficacy and safety of atezolizumab in combination with tiragolumab compared with durvalumab in participants with locally advanced, unresectable Stage III non-small cell lung cancer (NSCLC) who have received at least two cycles of concurrent platinum-based chemoradiotherapy (CRT) and have not had …

lung carcinoma
stage iii non-small cell lung cancer
cancer chemotherapy
chemoradiotherapy
durvalumab
Tauranga Hospital
 (3.2 away) Contact site
  • 0 views
  • 24 Jul, 2022
  • +177 other locations
A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis (STARSCAPE-OLE)

This study will evaulate the long-term safety, efficacy and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, administered by intravenous (IV) infusion to participants with idiopathic pulmonary fibrosis (IPF).

idiopathic pulmonary fibrosis
prm-151
Tauranga Hospital
 (3.2 away) Contact site
  • 23 views
  • 24 Jul, 2022
  • +139 other locations