Hamilton, Waikato, New Zealand Clinical Trials

A listing of Hamilton, Waikato, New Zealand clinical trials actively recruiting patients volunteers.

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Found 43 clinical trials
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis (QUASAR)

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Waikato Hospital
 (1.1 away) Contact site
  • 422 views
  • 28 Jul, 2022
  • +191 other locations
Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex (ENCORE)

The main objective of this study is to evaluate the efficacy of ALIS (amikacin liposome inhalation suspension) + background regimen (azithromycin [AZI] + ethambutol [ETH]) compared to the ELC (empty liposome control) + background regimen on participant-reported respiratory symptoms at Month 13.

NZL002
 (1.3 away) Contact site
  • 52 views
  • 28 Jul, 2022
  • +163 other locations
Phase 2b Study of ASLAN004 in Adults With Moderate-to-Severe Atopic Dermatitis

Phase 2b study designed to evaluate the efficacy and safety of ASLAN004 in adult patients with moderate-to-severe Atopic Dermatitis (AD) who are candidates for systemic therapy. This study will have 5 treatment arms (4 active and 1 placebo).

topical agents
corticosteroids
topical corticosteroid
Clinical Trials NZ
 (1.3 away) Contact site
  • 9 views
  • 29 Jul, 2022
  • +39 other locations
Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households

Otherwise healthy index patients (IP) are randomized to either baloxavir marboxil or placebo if their influenza symptoms onset was within 48 hours of screening. Their households are enrolled within 24 hours of randomization if at least 1 household contacts (HHC) have not received influenza vaccine within 6 months of screening …

baloxavir marboxil
headache
cough
PCR test
oseltamivir
Lakeland Clinical Trials Waikato
 (1.5 away) Contact site
  • 342 views
  • 29 Jul, 2022
  • +167 other locations
A Study to Evaluate the Change in Disease State and Adverse Events in Adult Participants With Polymyalgia Rheumatica (PMR) Dependent on Glucocorticoid Treatment, Receiving Subcutaneous Injections of ABBV-154 (AIM-PMR)

Polymyalgia rheumatica (PMR) is an inflammatory disease causing shoulder, hip, and neck pain and stiffness, in adults aged 50 years or older. This study evaluates how safe and effective ABBV-154 is in participants with glucocorticoid-dependent PMR. Adverse events and change in disease activity will be assessed. ABBV-154 is an investigational …

Waikato Hospital /ID# 229047
 (1.3 away) Contact site
  • 114 views
  • 29 Jul, 2022
  • +97 other locations
A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis (SELECT-GCA)

This study consists of two periods. The objective of Period 1 is to evaluate the efficacy of upadacitinib in combination with a 26-week corticosteroid (CS) taper regimen compared to placebo in combination with a 52-week CS taper regimen, as measured by the proportion of participants in sustained remission at Week …

Waikato Hospital /ID# 201944
 (1.3 away) Contact site
  • 405 views
  • 09 Aug, 2022
  • +122 other locations
Safety and Efficacy of AT-1501 in Patients With IgA Nephropathy (IgAN)

This is a phase 2a, multicenter, open-label study designed to evaluate the safety and efficacy of AT-1501 in patients with biopsy proven IgAN and at least 0.75 g/24 hours of protein in their urine at the time of screening.

fibrosis
kidney biopsy
monoclonal antibodies
nephropathy
Hawke's Bay Hospital
 (152.6 away) Contact site
  • 0 views
  • 08 Aug, 2022
  • +10 other locations
A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer (CheckMate 7DX)

The purpose of this study is to assess the safety and effectiveness of nivolumab with docetaxel in men with advanced castration resistant prostate cancer who have progressed after second-generation hormonal manipulation.

gonadotropin
tumor progression
metastatic castration-resistant prostate cancer
metastasis
endocrine therapy
Local Institution - 0101
 (1.3 away) Contact site
  • 16 views
  • 28 Jul, 2022
  • +263 other locations
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who roll-over into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. …

mk-3475
major surgery
pembrolizumab
metastasis
Waikato Hospital ( Site 1502)
 (1.3 away) Contact site
  • 755 views
  • 09 Aug, 2022
  • +323 other locations
The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions

The objective of this clinical trial is to evaluate the safety, effectiveness and performance of the DESyne BDS Plus Drug Eluting Coronary Stent System (DESyne BDS Plus DECSS) (Test) as compared to the CE Mark approved DESyne X2 Novolimus Eluting Coronary Stent System (DESyne X2 NECSS; DESyne X2) (Control) in …

stenosis
sirolimus
bypass graft
percutaneous coronary intervention
chest pain
North Shore Hospital
 (70.5 away) Contact site
  • 0 views
  • 10 Apr, 2022
  • +5 other locations