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Rotterdam, Netherlands Clinical Trials

A listing of Rotterdam, Netherlands clinical trials actively recruiting patients volunteers.

RESULTS

Found (352) clinical trials

Dislocated Stable Distal Both-Bone Forearm Fractures in Children

children who arrive at the emergency unit with a dislocated both-bone distal forearm fracture will be asked to join the trial. After informed consent, a randomization between 2 kinds of treatment will be done: K-wire fixation or no K-wire fixation of the fracture after a stable reposition. Outpatient clinic visits ...

Phase N/A

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Undislocated Distal Both-Bone Forearm Fractures in Children

children who arrive at the emergency unit with a undislocated both-bone distal forearm fracture will be asked to join the trial. After informed consent, a randomization between 2 kinds of cast will be done. Outpatient clinic visits till a follow-up of 6 months. During these visits we will investigate: consolidation ...

Phase N/A

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Treatment of Stable Both-Bone Midshaft Forearm Fractures in Children

children who arrive at the emergency unit with a stable both-bone midshaft forearm fracture will be asked to join the trial. If the fracture will be stable during reposition in the operating room, a randomization between 2 kinds of plaster treatment will be done. Outpatient clinic visits till a follow-up ...

Phase N/A

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Diagnostic Properties of Aldosterone-Renin Ratio in Primary Aldosteronism Among Hypertensives.

Although primary aldosteronism (PA) was formerly seen as a rare cause of hypertension, this condition is now thought to be the commonest cause of secondary hypertension, with the prevalence ranging up to 10-15 % of all hypertensives. Identification of patients with PA allows for specific treatment, for instance unilateral adrenalectomy ...

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Surgery or Noninvasive Therapy for Varicose Veins

Inclusion criteria: - Ultrasound confirmed GSV insufficiency (reflux time >0.5 second and vein diameter ≥0.5 cm) - non-treated GSV varicosis - CEAP -classification > C2 and As2 - >18 years old - Informed consent. Exclusion criteria: - Acute venous thrombosis / phlebitis - Absence of deep venous system - Vascular ...

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3T MRI CIED Post-Approval Study

The purpose of this study is to evaluate product performance of Magnetic Resonance (MR) Conditional Cardiac Implantable Electronic Devices (CIED) following 3 tesla (3T) MRI exposure. This will be achieved by evaluating the changes in pacing capture threshold (PCT) measurements following 3T MRI scan exposure. This study is required by ...

Phase N/A

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Phase I of SGM-101 in Patients With Cancer of the Colon Rectum or Pancreas

Surgery is the most important therapy for patients with cancer of the colon, rectum or pancreas. Complete resection, which is a crucial factor in the prognosis of a patient, is challenging as surgeons have to rely on visual appearance and palpation to discriminate between tumor and normal tissue. Carcinoembryonic antigen ...

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PROCLAIM-CX-072: A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered intravenously (IV) as a single agent or in combination with ipilimumab or vemurafenib in adult subjects with advanced or recurrent solid tumors or lymphomas. PROCLAIM-CX-072: PRObody ...

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Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen

The study objective is to determine in a high bleeding risk patient population undergoing PCI under standardized treatment (within current guidelines and instructions for use and including the bioresorbable polymer coated Ultimaster sirolimus-eluting stent), whether abbreviated DAPT is non-inferior to prolonged DAPT regimen in terms of NACE within 12 months, ...

Phase N/A

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Study of Pembrolizumab (MK-3475) or Placebo With Chemoradiation in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-412/KEYNOTE-412)

The purpose of this study is to determine the efficacy and safety of pembrolizumab given concomitantly with chemoradiation (CRT) and as maintenance therapy versus placebo plus CRT in participants with locally advanced head and neck squamous cell carcinoma (LA HNSCC). The primary hypothesis is that pembrolizumab in combination with CRT ...

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