Heeze, Netherlands Clinical Trials

A listing of Heeze, Netherlands clinical trials actively recruiting patients volunteers.

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Found 27 clinical trials
Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

The purpose of this study is to evaluate the effect of treatment with omecamtiv mecarbil compared with placebo on exercise capacity as determined by cardiopulmonary exercise testing following 20 weeks of treatment with omecamtiv mecarbil or placebo

Maxima Medisch Centrum Veldhoven
 (6.9 away) Contact site
  • 62 views
  • 20 Jun, 2021
  • +80 other locations
Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer

Given the uncertain benefit in efficacy of adding CDK 4/6 to first rather than second line endocrine treatment, the aim of this project is to evaluate whether the sequence of an aromatase inhibitor plus CDK 4/6 in first line followed by fulvestrant in second line is superior to the sequence …

gilbert's syndrome
metastasis
progesterone
endocrine therapy
breast cancer
St. Anna Ziekenhuis
 (3.0 away) Contact site
  • 71 views
  • 23 Jan, 2021
  • +71 other locations
Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)

The purpose of this study is to determine if patiromer treatment of subjects who developed hyperkalemia while receiving RAASi medications will result in continued use of RAASi medications in accordance with heart failure (HF) treatment guidelines and thereby decrease the occurrence of the combined endpoint of cardiovascular (CV) death and …

Investigator Site 36-013
 (7.5 away) Contact site
  • 37 views
  • 08 Jun, 2021
  • +484 other locations
Nortriptyline for the Treatment of Functional Dyspepsia

Functional dyspepsia (FD) is a common functional gastrointestinal disorder characterized by upper abdominal discomfort/pain and/or symptoms of meal-related fullness/satiety. There is currently no definitive therapy that is beneficial for all FD patients. Accumulating evidence suggests efficacy of tricyclic antidepressants (TCAs) in FD. However, no firm conclusion can be drawn currently …

endoscopy
discomfort
proton pump inhibitors
organic disease
tricyclic antidepressants
MMC
 (7.7 away) Contact site
  • 187 views
  • 22 Jan, 2021
  • +11 other locations
Induction Chemotherapy for Locally Recurrent Rectal Cancer

This is a multicentre, open-label, parallel arms, phase IIII study that randomises patients with locally recurrent rectal cancer in a 1:1 ratio to receive either induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery (experimental arm) or neoadjuvant chemoradiotherapy and surgery alone (control arm)

Catharina Hospital
 (7.3 away) Contact site
  • 0 views
  • 16 May, 2021
  • +8 other locations
A Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients

The purpose of this study is to determine whether acetylsalicylic acidis effective on the recurrence and survival of colon cancer patients.

Catharina Ziekenhuis
 (6.2 away) Contact site
  • 33 views
  • 23 Jan, 2021
  • +33 other locations
Treatment Strategies in Colorectal Cancer Patients With Initially Unresectable Liver-only Metastases

Colorectal cancer patients with initially unresectable liver-only metastases may be cured after downsizing of metastases by neoadjuvant systemic therapy. However, the optimal neoadjuvant induction regimen has not been defined, and no consensus exist on criteria for resectability. In this study colorectal cancer patients with initially unresectable liver-only metastases, as prospectively …

liver surgery
metastasis
systemic therapy
neutrophil count
bevacizumab
St. Anna Ziekenhuis
 (3.0 away) Contact site
  • 177 views
  • 23 Jan, 2021
  • +63 other locations
A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

This is a 2 part study. Part 1 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab versus placebo plus carboplatin-paclitaxel followed by placebo; and Part 2 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab plus niraparib versus placebo …

metastasis
liver metastasis
carboplatin/paclitaxel
measurable disease
serum pregnancy test
GSK Investigational Site
 (7.3 away) Contact site
  • 78 views
  • 30 Apr, 2021
  • +152 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

stroke
chronic disease
semaglutide
Novo Nordisk Investigational Site
 (6.3 away) Contact site
  • 1276 views
  • 20 Jun, 2021
  • +555 other locations
Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

The purpose of this study is to assess the efficacy and safety of the combination of pembrolizumab (MK-3475) and enzalutamide in the treatment of men with metastatic castration-resistant prostate cancer (mCRPC) who have not received chemotherapy for mCRPC, are abiraterone-nave, or are intolerant to or progressed on abiraterone acetate. There …

metastasis
abiraterone
diphosphonates
castration-resistant prostate cancer
bisphosphonate
Catharina Ziekenhuis ( Site 0472)
 (7.3 away) Contact site
  • 487 views
  • 20 Jun, 2021
  • +241 other locations