Heeze, Netherlands Clinical Trials

A listing of Heeze, Netherlands clinical trials actively recruiting patients volunteers.

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Found 121 clinical trials
The Feasibility and Clinical Efficacy of Atezolizumab Consolidation Treatment in High Risk (IPI > 2) DLBCL

The prognosis of Diffuse Large B cell Lymphoma (DLBCL) patients with an early relapse is dismal. Atezolizumab has shown promising activity in relapsed DLBCL patients. Toxicity data on atezolizumab are available for > 6000 patients and is manageable. The assumption of this study is that atezolizumab consolidation will result in …

b-cell lymphoma
rituximab
positron emission tomography
vincristine
doxorubicin
Catharina Ziekenhuis
 (6.2 away) Contact site
  • 37 views
  • 01 Apr, 2021
  • +64 other locations
Sexual Rehabilitation Programme After Radiotherapy for Gynaecological Cancer

The aim of this randomized controlled trial is to demonstrate that a nurse-led sexual rehabilitation intervention significantly improves sexual recovery and functioning among gynaecological cancer (GC) patients treated with radiotherapy (RT), compared with usual care (i.e., oral information by a nurse or doctor and written information). Women with GC (n=220) …

vaginal carcinoma
primary cancer
cancer of the cervix
cancer
Catharina Hospital
 (6.2 away) Contact site
  • 12 views
  • 24 Jan, 2021
  • +7 other locations
Morphine or Fentanyl for Refractory Dyspnea in COPD

Rationale: The most important complaint in severe COPD is dyspnea which is associated with a diminished exercise tolerance, reduced quality of life and can lead to anxiety and depression. If dyspnea continues to exist despite optimal therapy it is called refractory dyspnea. There is evidence that morphine is effective and …

dyspnea
prednisone
combinations
Elkerliek Ziekenhuis
 (7.5 away) Contact site
  • 29 views
  • 16 May, 2021
  • +9 other locations
Self-testing for HCV Re-infection in MSM

HIV+MSM (men who have sex with men) that have been cured of a hepatitis C viral infection (HCV) are at risk for HCV re-infection (5-10% per year). One intervention to reduce HCV incidence in this population may be to decrease the time to diagnosis of HCV re-infections in order to …

Catharina Ziekenhuis Eindhoven
 (6.2 away) Contact site
  • 17 views
  • 23 Jan, 2021
  • +6 other locations
DA-EPOCH-R Induction Followed by Nivolumab Consolidation in Newly Diagnosed MYC BCL2 and/or BCL6 Rearranged HGBL

The prognosis of patients with "high-grade B cell lymphoma with cellular myelocytomatosis (MYC) and B cell lymphoma 2 (BCL2) and/or B cell lymphoma 6 (BCL6) rearrangements" (double hit (DH)/triple hit (TH)-HGBL) with rituximab-CHOP (R-CHOP) is dismal as compared to patients with diffuse large B cell lymphoma (DLBCL) without MYC, BCL2 …

b-cell lymphoma
rituximab
vincristine
etoposide
measurable disease
Maxima MC
 (6.2 away) Contact site
  • 26 views
  • 26 Jan, 2021
  • +25 other locations
Pharmacogenetics Use For Further Treatment Improvement in childreN

There is large heterogeneity in treatment response to asthma medication and a one-size fits all approach based on current guidelines might not fit all children with asthma. It is expected that children with one or more variant alleles (Arg16Arg and Arg16Gly) within the beta2 adrenergic receptor (ADRB2) gene coding for …

Catharina ziekenhuis
 (7.3 away) Contact site
  • 6 views
  • 01 May, 2021
  • +22 other locations
Liposomal iRInotecan Carboplatin or oXaliplatin for Esophagogastric Cancer

This is a multi-center, open label, randomized phase II trial for patients with previously untreated metastatic or locally advanced esophagogastric cancer, using a pick the winner design to identify the best combination therapy in terms of progression free survival and neurotoxicity.

carboplatin
adenocarcinoma
serum pregnancy test
HER2
measurable disease
Catherina Ziekenhuis
 (6.2 away) Contact site
  • 5 views
  • 30 Jan, 2021
  • +14 other locations
Tolerability and Efficacy of Midostaurin to 10-day Decitabine in Unfit Adult AML and High Risk MDS Patients

The aim of this study is to investigate how safe and effective the addition of the new medicine midostaurin to decitabine is for the treatment of unfit acute myeloid leukemia (AML) and high-risk myelodysplasia (MDS) patients. Patients who are ineligible for intensive chemotherapy because of accompanying diseases may opt for …

decitabine
leukemia
secondary acute myeloid leukemia
gilbert's syndrome
acute promyelocytic leukemia
Catharina Ziekenhuis
 (6.2 away) Contact site
  • 6 views
  • 23 Jan, 2021
  • +20 other locations
Evidence Based Information Provision to Improve Decision Making After Oesophagogastric Cancer Diagnosis (SOURCE)

The overarching aim of the programme 'Stimulating evidence based, personalized and tailored information provision to improve decision making after oesophagogastric cancer diagnosis' (SOURCE) is to provide oesophagogastric cancer patients at all disease stages with evidence based and personalized information about survival, treatment-related side-effects and/or complications and health related quality of …

gastric cancer
cancer
Catherina Ziekenhuis
 (6.2 away) Contact site
  • 4 views
  • 24 Jan, 2021
  • +11 other locations
Doxapram Therapy in Preterm Infants (DOXA Trial)

Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system. AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system. In order to prevent oxygen shortage, …

continuous positive airway pressure
assisted ventilation
mechanical ventilation
pulmonary disease
Maxima Medical Center Veldhoven
 (6.9 away) Contact site
  • 0 views
  • 25 Jan, 2021
  • +17 other locations