Heeze, Netherlands Clinical Trials

A listing of Heeze, Netherlands clinical trials actively recruiting patients volunteers.

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Found 122 clinical trials
A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma or Malignant Pheochromocytoma/Paraganglioma

This is a multicenter, Phase 1/2, First-In-Human study to assess the safety, tolerability, immunogenicity, and preliminary efficacy of EO2401 in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma.

measurable disease
adrenal pheochromocytoma
M xima Medisch Centrum
 (6.1 away) Contact site
  • 28 Jan, 2021
  • +6 other locations
A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

The main aims of the study are: To check for side effects from TAK-994 and check what dose of TAK-994 participants can tolerate. To check what dose range provides adequate relief of narcolepsy symptoms. To check how much TAK-994 stays in the blood of participants, over time. The study will …

Kempenhaeghe, Heeze
 (1.2 away) Contact site
  • 20 Jun, 2021
  • +105 other locations
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome (MDS) is a group of disorders that gradually affect the ability of a person's bone marrow (semi-liquid tissue present in many bones like backbones) to produce normal blood cells. Some people with MDS have a risk of the disease progressing to acute myeloid leukemia (AML), and a risk …

myeloid leukemia
Maxima Medisch Centrum /ID# 223010
 (6.2 away) Contact site
  • 13 Jun, 2021
  • +266 other locations
Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the Netherlands

Digoxin is the oldest, market-authorized drug for heart failure (HF), and very cheap. A large trial with digoxin, the DIG trial, executed in the early nineties revealed a highly significant reduction in HF hospitalizations, but no effect on mortality. A post-hoc analysis of the DIG trial suggests that low serum …

heart failure
b-type natriuretic peptide
chronic heart failure
Elkerliek Ziekenhuis
 (7.6 away) Contact site
  • 12 Mar, 2021
  • +38 other locations
PSMA-PET Guided Hypofractionated Salvage Prostate Bed Radiotherapy

After radical prostatectomy approximately 15-40% of men develop a biochemical recurrence (BR) within 5 years. The standard treatment of post-prostatectomy BR is salvage external beam radiation therapy (sEBRT). sEBRT can provide long-term disease control; with 5 year biochemical progression-free survival (bPFS) up to 60% and with most treatment failures in …

 (6.2 away) Contact site
  • 12 Jun, 2021
  • +11 other locations
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

diuretic therapy
heart failure
heart disease
ejection fraction
Maxima Medisch Centrum, locatie Veldhoven
 (6.9 away) Contact site
  • 22 May, 2021
  • +761 other locations
Effect of Automated Closed-Loop Ventilation Versus Conventional Ventilation on Duration and Quality of Ventilation

INTELLiVENT-Adaptive Support Ventilation (ASV) is a fully automated closed-loop mode of mechanical ventilation available on commercial ventilators. Evidence for clinical benefit of INTELLiVENT-ASV in comparison to non-automated ventilation is lacking. The ACTiVE study is an international, multicenter, randomized controlled trial in invasively ventilated ICU patients with the objective to compare …

Catharina Ziekenhuis
 (6.2 away) Contact site
  • 25 Jan, 2021
  • +12 other locations
Spironolactone In The Treatment of Heart Failure

The purpose of this study is to determine whether the treatment of patients with HFmrEF and HFpEF at high risk of cardiovascular events with the mineralocorticoid receptor antagonist (MRA) spironolactone reduces a composite of recurrent heart failure hospitalizations and cardiovascular mortality.

Elkerliek Ziekenhuis
 (7.6 away) Contact site
  • 03 Feb, 2021
  • +62 other locations
A Phase II Randomized Double-blind Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis

This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult subjects with Chronic Obstructive Pulmonary Disease and Chronic Bonchitis.

Research site
 (6.2 away) Contact site
  • 20 Jun, 2021
  • +92 other locations
A Study of TAR-200 in Combination With Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

The purpose of this study is to evaluate the overall complete response (CR) rate in participants treated with TAR-200 in combination with cetrelimab (Cohort 1), or TAR-200 alone (Cohort 2), or cetrelimab alone (Cohort 3) with Carcinoma in Situ (CIS), with or without concomitant high-grade Ta or T1 papillary disease.

intravesical bcg
transurethral resection
invasive bladder cancer
Catharina Ziekenhuis
 (7.3 away) Contact site
  • 28 May, 2021
  • +174 other locations