Heeze, Netherlands Clinical Trials

A listing of Heeze, Netherlands clinical trials actively recruiting patients volunteers.

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Found 122 clinical trials
HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

This study will evaluate the efficacy and safety of vutrisiran 25 mg administered subcutaneously (SC) once every 3 months (q3M) compared to placebo in patients with ATTR amyloidosis with cardiomyopathy.

Clinical Trial Site
 (6.2 away) Contact site
  • 20 Jun, 2021
  • +91 other locations
PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer

This is prospective, multicenter, randomised phase III trial among women with endometrial cancer with high-intermediate risk features to investigate the role of an integrated clinicopathological and molecular risk profile to determine if participants should receive no adjuvant therapy, vaginal brachytherapy or external beam radiotherapy based on a favourable, intermediate or …

Catharina Hospital
 (6.2 away) Contact site
  • 23 Jan, 2021
  • +25 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

acute coronary syndrome
percutaneous coronary intervention
myocardial infarction
arterial disease
5280040 - Maxima Medisch Centrum
 (6.3 away) Contact site
  • 20 Jun, 2021
  • +3422 other locations
The Impact of a Nutritional Supplement (Impryl ) on Male Fertility

Infertility is a worldwide problem and about 10%-15% of all couples will be affected by the inability to have children. In approximately 50% of infertile couples a male factor is involved. Male infertility is of multifactorial origin. In the past decade, the role of oxidative stress on sperm has been …

M xima Medisch Centrum
 (6.9 away) Contact site
  • 24 Jan, 2021
  • +17 other locations
Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase

Study should demonstrate that alkaline phosphatase reduces the incidence and extent of acute kidney injury after cardiopulmonary bypass (CPB) as defined by the AKIN criteria.

Catharina Ziekenhuis, Cathreine R&D, Heartcentre
 (7.3 away) Contact site
  • 25 Jan, 2021
  • +15 other locations
Management of Low-risk (Grade I and II) DCIS

A substantial number of DCIS lesions will never form a health hazard, particularly if it concerns slow-growing low-risk DCIS (grade I and II). This implies that many women might be unnecessarily going through intensive treatment resulting in a decrease in quality of life and an increase in health care costs, …

estrogen receptor
breast cancer
hormone therapy
Catharina Ziekenhuis
 (6.2 away) Contact site
  • 17 Feb, 2021
  • +44 other locations
Early Treatment Versus Expectative Management of PDA in Preterm Infants

Much controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants, especially in those born at a gestational age <28 weeks and/or a birth weight 1000 grams due to a lack of evidence for or against different approaches. A PDA has been associated with serious …

bronchopulmonary dysplasia
necrotizing enterocolitis
Maxima Medical Center
 (7.7 away) Contact site
  • 24 Jan, 2021
  • +13 other locations
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care physical therapy for hip and knee arthroplasty.

partial knee replacement
hip arthroplasty
total knee replacement
St. Annaziekenhuis
 (3.0 away) Contact site
  • 15 Jun, 2021
  • +32 other locations
An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)

This is a Phase 3, prospective, open-label, international, multicentre study of Flurpiridaz (18F) Injection for PET MPI in patients referred for ICA because of suspected CAD.

Catharina Hospital
 (7.3 away) Contact site
  • 27 Jan, 2021
  • +57 other locations
PeRcutaneous cOronary Intervention of Native Coronary arTery Versus Venous Bypass Graft in Patients With Prior CABG

Multi-centre, randomised clinical trial with anticipated 17 European centres: in the Netherlands, Belgium, Germany and UK. Patients with a dysfunctional bypass graft with a clinical indication for revascularization will be randomized to either PCI of the native vessel or PCI of the dysfunctional venous bypass graft. 584 patients with a …

coronary disease
percutaneous coronary intervention
Catharina Ziekenhuis
 (6.2 away) Contact site
  • 25 Jan, 2021
  • +15 other locations