Heeze, Netherlands Clinical Trials

A listing of Heeze, Netherlands clinical trials actively recruiting patients volunteers.

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Found 122 clinical trials
14022 ATTUNE Cementless RP Clinical Performance Evaluation

The primary objective of this study is to examine the change from pre-operative baseline to two year postoperative functional performance improvement for the ATTUNE primary, cementless TKA RP system as measured with the KOOS questionnaire (KOOS-ADL sub-score). This will be carried out for two configurations: cruciate retaining rotating platform (ATTUNE …

total knee replacement
joint reconstruction
Elkerliek Ziekenhuis
 (7.5 away) Contact site
  • 0 views
  • 20 Jun, 2021
  • +33 other locations
The Drug Rediscovery Protocol (DRUP Trial)

This is a prospective, non-randomized clinical trial that aims to describe the efficacy and toxicity of commercially available, targeted anticancer drugs* prescribed for treatment of patients with advanced cancer with a potentially actionable variant as revealed by a genomic or protein expression test. The study also aims to simplify patient …

trametinib
erlotinib
solid tumor
primary tumor
metastatic solid tumor
Maxima Medisch Centrum
 (6.3 away) Contact site
  • 260 views
  • 18 Mar, 2021
  • +34 other locations
Prospective Endoscopic Follow-up of Patients With Submucosal Esophageal Adenocarcinoma (The PREFER Trial)

Aim of this prospective multicenter study is to evaluate the safety of an endoscopic follow-up strategy in patients treated with endoscopic resection (ER) for submucosal or high-risk mucosal esophageal adenocarcinoma (T1bN0M0 or HR T1aN0M0 EAC).

adenocarcinoma
esophageal adenocarcinoma
endoscopic resection
Catharina Hospital
 (6.2 away) Contact site
  • 37 views
  • 29 Jan, 2021
  • +18 other locations
A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

This is a 2 part study. Part 1 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab versus placebo plus carboplatin-paclitaxel followed by placebo; and Part 2 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab plus niraparib versus placebo …

carboplatin
paclitaxel
anticoagulant
recurrent disease
aptt
GSK Investigational Site
 (7.3 away) Contact site
  • 78 views
  • 30 Apr, 2021
  • +152 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

chronic disease
semaglutide
stroke
Novo Nordisk Investigational Site
 (6.3 away) Contact site
  • 1276 views
  • 20 Jun, 2021
  • +555 other locations
Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

The purpose of this study is to assess the efficacy and safety of the combination of pembrolizumab (MK-3475) and enzalutamide in the treatment of men with metastatic castration-resistant prostate cancer (mCRPC) who have not received chemotherapy for mCRPC, are abiraterone-nave, or are intolerant to or progressed on abiraterone acetate. There …

serum testosterone
bisphosphonate
orchiectomy
androgens
adenocarcinoma of prostate
Catharina Ziekenhuis ( Site 0472)
 (7.3 away) Contact site
  • 487 views
  • 20 Jun, 2021
  • +241 other locations
Tezepelumab COPD Exacerbation Study

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 2a Study to Explore the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

ct scan
bronchodilator
severe chronic obstructive pulmonary disease
copd exacerbation
Research Site
 (7.3 away) Contact site
  • 130 views
  • 16 May, 2021
  • +106 other locations
Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients

The purpose of this study is to support the dose selection for future studies by evaluating efficacy and safety of different QBW251 doses in COPD patients with chronic bronchitis and a history of exacerbations, compared to placebo, when added to a triple combination therapy of LABA, LAMA and ICS with …

bronchitis
Novartis Investigative Site
 (7.3 away) Contact site
  • 176 views
  • 20 Jun, 2021
  • +173 other locations
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

adenocarcinoma
cancer
antiandrogen therapy
apalutamide
prostatectomy
Catharinaziekenhuis
 (7.3 away) Contact site
  • 291 views
  • 02 Jun, 2021
  • +352 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

myocardial infarction
diabetes
infarct
arterial disease
stroke
Research Site
 (7.3 away) Contact site
  • 536 views
  • 20 Jun, 2021
  • +1330 other locations