Heeze, Netherlands Clinical Trials

A listing of Heeze, Netherlands clinical trials actively recruiting patients volunteers.

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Found 122 clinical trials
Nortriptyline for the Treatment of Functional Dyspepsia

Functional dyspepsia (FD) is a common functional gastrointestinal disorder characterized by upper abdominal discomfort/pain and/or symptoms of meal-related fullness/satiety. There is currently no definitive therapy that is beneficial for all FD patients. Accumulating evidence suggests efficacy of tricyclic antidepressants (TCAs) in FD. However, no firm conclusion can be drawn currently …

proton pump inhibitors
tricyclic antidepressants
functional gastrointestinal disorder
 (7.7 away) Contact site
  • 22 Jan, 2021
  • +11 other locations
Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy

Rationale The combination of ipilimumab and nivolumab induces relatively high response rates and promising response depth in late stage melanoma. Nevertheless, it takes time till responses occur and still a significant number of patients do not benefit from treatment, due to rapid progressive disease or resistance to therapy. In contrast …

Maxima MC
 (6.2 away) Contact site
  • 24 Jan, 2021
  • +12 other locations
Hernia Exploration oR Not In Infants Analysis

This study evaluates the effectiveness and cost-effectiveness of contralateral surgical exploration during unilateral inguinal hernia repair in children younger than six months with a unilateral inguinal hernia. In half of the participants contralateral exploration will be performed, while in the other half only unilateral inguinal hernia repair will be performed.

repair of inguinal hernia
M xima Medical Center
 (7.7 away) Contact site
  • 24 Jan, 2021
  • +5 other locations
Induction Chemotherapy for Locally Recurrent Rectal Cancer

This is a multicentre, open-label, parallel arms, phase IIII study that randomises patients with locally recurrent rectal cancer in a 1:1 ratio to receive either induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery (experimental arm) or neoadjuvant chemoradiotherapy and surgery alone (control arm)

Catharina Hospital
 (7.3 away) Contact site
  • 16 May, 2021
  • +8 other locations
Postbariatric EArly Discharge Controlled by Healthdot

This clinical investigation is a single center patient preference trial in a tertiary hospital in the Netherlands, designed to compare the outcome of two different recovery paths after standard of care bariatric surgery. The difference between both recovery paths is that half of the patients will get the standard of …

Catharina Hospital
 (7.3 away) Contact site
  • 28 Apr, 2021
  • 1 location
A Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients

The purpose of this study is to determine whether acetylsalicylic acidis effective on the recurrence and survival of colon cancer patients.

Catharina Ziekenhuis
 (6.2 away) Contact site
  • 23 Jan, 2021
  • +33 other locations
Treatment Strategies in Colorectal Cancer Patients With Initially Unresectable Liver-only Metastases

Colorectal cancer patients with initially unresectable liver-only metastases may be cured after downsizing of metastases by neoadjuvant systemic therapy. However, the optimal neoadjuvant induction regimen has not been defined, and no consensus exist on criteria for resectability. In this study colorectal cancer patients with initially unresectable liver-only metastases, as prospectively …

liver surgery
systemic therapy
folfiri regimen
St. Anna Ziekenhuis
 (3.0 away) Contact site
  • 23 Jan, 2021
  • +63 other locations
Nivolumab With Gemcitabine Oxaliplatin + Rituximab in r/r Elderly Lymphoma Patients

This study evaluates the addition of nivolumab to gemcitabine, oxaliplatin plus rituximab in case of B-cell lymphoma

aggressive non-hodgkin's lymphoma
b-cell lymphoma
hodgkin's disease
Maxima Medisch Centrum
 (6.2 away) Contact site
  • 02 Feb, 2021
  • +124 other locations
Neoadjuvant Study Using Trastuzumab or Trastuzumab With Pertuzumab in Gastric or Gastroesophageal Junction Adenocarcinoma

The purpose of this study is to find out whether either trastuzumab or the combination of trastuzumab and pertuzumab with standard chemotherapy shows more activity against gastro-oesophageal adenocarcinoma than standard chemotherapy given before and after surgery and it can be safely administered.

adenocarcinoma of esophagus
Catharina Ziekenhuis
 (6.2 away) Contact site
  • 22 Jan, 2021
  • +38 other locations
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

This study aims to determine if treatment with apixaban, compared with aspirin, will reduce the risk of ischemic stroke and systemic embolism in patients with device-detected sub-clinical atrial fibrillation and additional risk factors for stroke.

atrial fibrillation
ischemic stroke
atrial flutter
M xima Medisch Centrum
 (6.9 away) Contact site
  • 26 Jan, 2021
  • +131 other locations