Enschede, Netherlands Clinical Trials

A listing of Enschede, Netherlands clinical trials actively recruiting patients volunteers.

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Found 62 clinical trials
Multicentric Randomised Trial for Resectable Gastric Cancer

The CRITICS-II trial aims to identify the optimal preoperative regimen in resectable gastric cancer by comparing three investigational treatment arms: chemotherapy vs. chemotherapy and subsequent chemoradiotherapy vs. chemoradiotherapy. The rationale behind this trial design is based on the following concepts: Preoperative treatment is associated with better patient compliance than postoperative …

docetaxel
gastrectomy
paclitaxel
gastric adenocarcinoma
laparoscopy
Ziekenhuisgroep Twente
 (13.8 away) Contact site
  • 6 views
  • 30 Jan, 2021
  • +28 other locations
ENdometrial Cancer SURvivors' Follow-up carE (ENSURE): Less is More?

Background: It has often been hypothesized that the frequency of follow-up for patients with early-stage endometrial cancer could be decreased. However, studies evaluating effects of a reduced follow-up schedule among this patient group are lacking. Objective: Assess patient satisfaction and cost-effectiveness of a less frequent follow-up schedule compared to the …

cancer
endometrial carcinoma
carcinoma
Streekziekenhuis Koningin Beatrix
 (18.0 away) Contact site
  • 69 views
  • 23 Jan, 2021
  • +46 other locations
Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases

This is a multicentre, open-label, parallel-group, phase II-III, superiority study that randomises patients with isolated resectable colorectal peritoneal metastases in a 1:1 ratio to receive either perioperative systemic therapy and cytoreductive surgery with HIPEC (experimental arm) or upfront cytoreductive surgery with HIPEC alone (control arm).

peritoneal metastases
metastasis
systemic therapy
laparotomy
measurable disease
Radboud University Medical Centre
 (51.5 away) Contact site
  • 76 views
  • 22 Jan, 2021
  • +9 other locations
Blinatumomab Added to Prephase and Consolidation Therapy in Precursor B-acute Lymphoblastic Leukemia in Adults.

Blinatumomab is a new active bispecific monoclonal antibody for treatment of lymphoid malignancies, including ALL (acute Lymphoblastic Leukemia ) whose activity for remission induction needs to be explored in combination with standardized treatment in order to improve outcome of this disease which is still lethal in most adult patients. Ultimate …

Isala
 (39.7 away) Contact site
  • 12 views
  • 25 Jan, 2021
  • +15 other locations
Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is a difficult to treat molecular subtype with a poor survival. TNBC can be divided into at least two molecular entities; BRCA-like and non-BRCA-like. In this trial we would like to investigate whether a molecular subgroup exists within TNBCs that derives a benefit from atezolizumab …

immunohistochemistry
metastasis
chromogenic in situ hybridization
paclitaxel
measurable disease
ZGT
 (13.2 away) Contact site
  • 36 views
  • 16 Jun, 2021
  • +48 other locations
Graft Selection in Anatomic Anterior Cruciate Ligament Reconstruction

A rupture of the anterior cruciate ligament (ACL) is a severe injury of the knee. The current gold Standard treatment for young and active patients with instability, is a surgical ACL reconstruction. However, there still is no consensus on which graft is best suited for this.The aim of the current …

anterior cruciate ligament reconstruction
swelling
ligament reconstruction
autograft
arthroscopy
OCON
 (4.9 away) Contact site
  • 34 views
  • 24 Jan, 2021
  • +1 other locations
Pharmacogenetics Use For Further Treatment Improvement in childreN

There is large heterogeneity in treatment response to asthma medication and a one-size fits all approach based on current guidelines might not fit all children with asthma. It is expected that children with one or more variant alleles (Arg16Arg and Arg16Gly) within the beta2 adrenergic receptor (ADRB2) gene coding for …

Medisch Spectrum Twente
 (0.3 away) Contact site
  • 6 views
  • 01 May, 2021
  • +22 other locations
Device-based Rate Versus Rhythm Control in Symptomatic Recent-onset Atrial Fibrillation (RACE 9 OBSERVE-AF)

Continuous heart rhythm monitoring elucidated the recurrent and transient nature of recent-onset atrial fibrillation (AF). The RACE7 ACWAS showed that a wait-and-see approach (WAS) in patients with recent-onset AF (rate control for symptom relief followed by delayed cardioversion if needed <48h) allows spontaneous conversion to sinus rhythm in 69% of …

Rijnstate
 (45.1 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • +12 other locations
Monitoring Spondyloarthritis With SpA-Net

Randomized controlled trial to assess the effectiveness and cost-effectiveness of an intervention combining patient initiated care and telemonitoring through the online eHealth platform SpA-Net versus standard care for patients with spondyloarthritis.

Maastricht University Medical Center
 (107.7 away) Contact site
  • 0 views
  • 28 Jan, 2021
  • +1 other locations
Endurant CHevAr New Indication Trial: ENCHANT

The purpose of the post-market study is to assess the clinical outcomes, safety, and performance of the Endurant Chimney Graft Technique (Endurant Stent Graft Systems used with a balloon-expandable covered stent graft) for treatment of juxtarenal aortic aneurysms with a short infrarenal neck in a real world setting.

aortic aneurysm
Medisch Spectrum Twente
 (0.5 away) Contact site
  • 37 views
  • 15 Jun, 2021
  • +45 other locations