Utsunomiya, Japan Clinical Trials

A listing of Utsunomiya, Japan clinical trials actively recruiting patients volunteers.

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Found 18 clinical trials
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

headache
migraine
Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 576 views
  • 01 Nov, 2020
  • +146 other locations
A Study Comparing Once-weekly vs Twice-weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Compare efficacy of 56 mg/m2 carfilzomib administered once-weekly in combination with lenalidomide and dexamethasone (KRd 56 mg/m2) to 27 mg/m2 carfilzomib administered twice-weekly in combination with lenalidomide and dexamethasone (KRd 27 mg/m2) in subjects with relapsed or refractory multiple myeloma (RRMM) with 1 to 3 prior lines of therapy.

Research Site
 (1.3 away) Contact site
  • 18 views
  • 24 Nov, 2020
  • +105 other locations
Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

The purpose of study is to evaluate if the addition of GSK3359609 to pembrolizumab as first-line treatment improves the efficacy of pembrolizumab in participants with recurrent or metastatic (R/M) head and neck squamous cell carcinoma/cancer (HNSCC). This is a randomized, double-blind, adaptive Phase II/III study comparing a combination of GSK3359609 …

squamous cell carcinoma
measurable disease
carcinoma
primary tumor
metastatic head and neck squamous cell carcinoma
GSK Investigational Site
 (6.5 away) Contact site
  • 6 views
  • 20 Nov, 2020
  • +166 other locations
Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.

This is an international, multicentre, parallel-group, event-driven, randomised, double-blind, placebo-controlled study in HFpEF patients, evaluating the effect of dapagliflozin 10 mg versus placebo, given once daily in addition to background regional standard of care therapy, including treatments to control co-morbidities, in reducing the composite of CV death or heart failure …

diuretics
hypertrophy
ventricular hypertrophy
diuretic therapy
Research Site
 (1.9 away) Contact site
  • 230 views
  • 27 Sep, 2020
  • +406 other locations
A Long-term Study to Assess the Safety and Efficacy of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP).

This is an open-label long-term multicenter phase 3 trial to evaluate the efficacy and safety of ARGX-113 in adult patients with primary ITP.

Investigator Site 14
 (8.2 away) Contact site
  • 0 views
  • 04 Nov, 2020
  • +44 other locations
Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer

JCOG1801 is a randomized phase III trial which was initiated in Japan in August 2019 to confirm the superiority of preoperative chemoradiotherapy followed by surgery plus adjuvant chemotherapy for local relapse-free survival over standard treatment, i.e. surgery plus adjuvant chemotherapy, for previously non-irradiated locally recurrent rectal cancer.

platelet count
metastasis
ct scan
measurable disease
neutrophil count
Tochigi Cancer Center
 (0.0 away) Contact site
  • 4 views
  • 11 Jun, 2020
  • +44 other locations
A Safety Extension Study of Ontamalimab in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease (AIDA)

The purpose of this study is to evaluate the safety and tolerability of long-term treatment with ontamalimab in participants with moderate to severe Ulcerative Colitis (UC) or Crohn's disease (CD).

endoscopy
flexible sigmoidoscopy
hematochezia
ulcerative colitis or crohn's
crohn's disease
Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 1349 views
  • 11 Nov, 2020
  • +793 other locations
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis

The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.

atopy
corticosteroids
eczema
topical corticosteroid
ly3009104
Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 102 views
  • 26 Nov, 2020
  • +180 other locations
This is a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS).

The purpose of this study is to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study will also assess the safety …

antiseptics
hidradenitis
abscess
secukinumab
Novartis Investigative Site
 (6.5 away) Contact site
  • 1025 views
  • 08 Oct, 2020
  • +121 other locations
Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trastuzumab in combination with SOC chemotherapy in participants with HER2-positive gastric cancer. The primary hypotheses of the study are that pembrolizumab plus trastuzumab in combination with chemotherapy is superior …

gastric cancer
measurable disease
cancer
immunohistochemistry
HER2
Tochigi Cancer Center ( Site 2627)
 (1.3 away) Contact site
  • 303 views
  • 27 Nov, 2020
  • +196 other locations