Utsunomiya, Japan Clinical Trials

A listing of Utsunomiya, Japan clinical trials actively recruiting patients volunteers.

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Found 28 clinical trials
Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International Multicentre Randomised-controlled Two-arm Assessor-blinded Trial

When to start anticoagulation in patients with an acute ischaemic stroke and atrial fibrillation (AF) is a relevant unanswered question in clinical practice. Direct oral anticoagulants (DOACs) are highly effective for secondary stroke prevention in these patients, but DOACs were never initiated <7 days after stroke onset in recent trials. …

atrial fibrillation
edoxaban
apixaban
stroke
ct scan
Jichi Medical University
 (0.7 away) Contact site
  • 370 views
  • 09 Jun, 2021
  • +114 other locations
Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trastuzumab in combination with SOC chemotherapy in participants with HER2-positive gastric cancer. The primary hypotheses of the study are that pembrolizumab plus trastuzumab in combination with chemotherapy is superior …

cancer chemotherapy
cancer
capecitabine
measurable disease
HER2
Tochigi Cancer Center ( Site 2627)
 (1.3 away) Contact site
  • 303 views
  • 13 Jun, 2021
  • +206 other locations
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis

The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.

corticosteroids
baricitinib
ly3009104
topical corticosteroid
atopy
Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 102 views
  • 13 Jun, 2021
  • +189 other locations
This is a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS).

The purpose of this study is to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study will also assess the safety …

abscess
antiseptics
secukinumab
hidradenitis
Novartis Investigative Site
 (6.5 away) Contact site
  • 1025 views
  • 09 Jun, 2021
  • +122 other locations
Phase III Trial of Stage I Ovarian Cancer After Surgery

To compare the Overall survival of adjuvant chemotherapy versus observation in stage I epithelial ovarian cancer after comprehensive staging surgery

Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 0 views
  • 23 Jan, 2021
  • +102 other locations
Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer

JCOG1801 is a randomized phase III trial which was initiated in Japan in August 2019 to confirm the superiority of preoperative chemoradiotherapy followed by surgery plus adjuvant chemotherapy for local relapse-free survival over standard treatment, i.e. surgery plus adjuvant chemotherapy, for previously non-irradiated locally recurrent rectal cancer.

neutrophil count
adenocarcinoma
carcinoma
platelet count
metastasis
Tochigi Cancer Center
 (0.0 away) Contact site
  • 4 views
  • 25 Jan, 2021
  • +44 other locations
A Study of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroids in Japanese Participants With Moderate-to-Severe Atopic Dermatitis

The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in combination with a topical corticosteroids in Japanese participants with atopic dermatitis.

Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 0 views
  • 15 May, 2021
  • +36 other locations
A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments

The purpose of this study is to evaluate the efficacy of ustekinumab in participants with active polymyositis (PM)/dermatomyositis (DM) despite receiving 1 or more standard-of-care treatments (for example, glucocorticoids and/or immunomodulators).

dermatomyositis
weakness
glucocorticoids
azathioprine
mycophenolate mofetil
Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 8 views
  • 25 Mar, 2021
  • +37 other locations
A Phase 3 Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of eculizumab in the treatment of pediatric refractory gMG based on change from Baseline in the Quantitative Myasthenia Gravis (QMG) score for disease severity.

weakness
serologic test
plasma exchange
immunosuppressive agents
acetylcholinesterase inhibitors
Dokkyo Medical University Hospital
 (6.5 away) Contact site
  • 18 views
  • 25 Jan, 2021
  • +13 other locations
KW-3357 Study in Patients With Early Onset Severe Preeclampsia

The purpose of this study is to evaluate the efficacy of intravenous KW-3357 in patients with early-onset severe preeclampsia by comparing the prolongation days of pregnancy with that of placebo.

hypertension
severe pre-eclampsia
Dokkyo Medical University Hospital
 (9.8 away) Contact site
  • 2 views
  • 26 Jan, 2021
  • +60 other locations