Suginami-ku, Japan Clinical Trials

A listing of Suginami-ku, Japan clinical trials actively recruiting patients volunteers.

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Found 20 clinical trials
Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab Followed by Maintenance Durvalumab Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients.

This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and bevacizumab followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian cancer.

Research Site
 (4.7 away) Contact site
  • 84 views
  • 16 Jun, 2021
  • +286 other locations
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix

The study will integrate the efficacy of combining the anti programmed death-ligand 1 (anti-PD-L1) agent atezolizumab with the current standard of care in Stage IVB , persistent or recurrent carcinoma of the cervix, namely cisplatin or carboplatin/paclitaxel/bevacizumab. It will be explored the combination of bevacizumab plus atezolizumab, with no patient …

Keio University Hospital
 (1.8 away) Contact site
  • 62 views
  • 26 Jan, 2021
  • +90 other locations
Atezolizumab Trial in Endometrial Cancer - AtTEnd

Atezolizumab is an engineered humanised monoclonal immunoglobulin G1 antibody that binds selectively to PD-L1 and prevents its interaction with PD-1 and B7-1. In May 2016 atezolizumab was approved by the FDA for patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following any platinum-containing chemotherapy, …

antineoplastic
endometrial carcinoma
recurrent endometrial cancer
monoclonal antibodies
transitional cell carcinoma
Keio University Hospital
 (1.8 away) Contact site
  • 495 views
  • 16 Jun, 2021
  • +106 other locations
Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

The purpose of this study is to assess the efficacy and safety of treatment with carboplatin/paclitaxel* PLUS pembrolizumab (MK-3475) and maintenance olaparib (MK-7339) in women with epithelial ovarian cancer (EOC), fallopian tube cancer, or primary peritoneal cancer. The primary study hypotheses are that the combination of pembrolizumab plus carboplatin/paclitaxel* followed …

excisional biopsy
debulking surgery
mk-3475
docetaxel
bevacizumab
Kyorin University Hospital ( Site 2610)
 (4.2 away) Contact site
  • 732 views
  • 16 Jun, 2021
  • +258 other locations
Neoadjuvant Hormonal Therapy Plus Palbociclib in Operable Hormone Sensitive and HER2-Negative Primary Breast Cancer

The study is a randomized, double blind, placebo controlled, Phase 3 clinical trial with the primary objective of demonstrating the efficacy of palbociclib in combination with Endocrine therapy over Endocrine therapy alone measured by PEPI and EndoPredict EPclin Score in women with operable HR+, HER2 negative breast cancer . The …

hormone therapy
endocrine therapy
neutrophil count
breast cancer
her-2
Kyorin University Hospital
 (4.2 away) Contact site
  • 43 views
  • 30 May, 2021
  • +26 other locations
Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST)

This implementation study aims to evaluate the efficacy, acceptability, and safety of first-trimester screening and prevention for preterm-preeclampsia. It is a multicenter stepped wedge cluster randomized trial including maternity / diagnostic units from ten regions in Asia. The study involves a period where no intervention will take place at all …

aspirin
maternity
Showa University Hospital
 (1.8 away) Contact site
  • 38 views
  • 02 Feb, 2021
  • +16 other locations
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

vaccination
lower respiratory tract infection
prenatal
National Hospital Organization Tokyo Medical Center
 (5.3 away) Contact site
  • 114 views
  • 03 Jun, 2021
  • +431 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

carcinoma
endometrial carcinoma
recurrent endometrial cancer
maintenance therapy
carboplatin
Research Site
 (3.2 away) Contact site
  • 104 views
  • 16 Jun, 2021
  • +192 other locations
Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047)

The purpose of this study is to evaluate the efficacy and safety of pembrolizumab plus concurrent chemoradiotherapy compared to placebo plus concurrent chemoradiotherapy in participants with locally advanced cervical cancer. The primary hypotheses are that pembrolizumab plus concurrent chemoradiotherapy is superior to placebo plus concurrent chemoradiotherapy with respect to progression-free …

adenocarcinoma
carcinoma
squamous cell carcinoma
external beam radiation therapy
brachytherapy
Kyorin University Hospital ( Site 1158)
 (4.2 away) Contact site
  • 85 views
  • 13 Jun, 2021
  • +154 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

hormone therapy
bevacizumab
topotecan
primary peritoneal carcinoma
metastasis
National Cancer Center Hospital
 (7.9 away) Contact site
  • 1729 views
  • 16 Jun, 2021
  • +211 other locations