Sakura, Japan Clinical Trials

A listing of Sakura, Japan clinical trials actively recruiting patients volunteers.

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Found 64 clinical trials
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
Toho University Sakura Medical Center /ID# 164254
 (0.0 away) Contact site
  • 604 views
  • 13 Jun, 2021
  • +772 other locations
Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)

The purpose of this study is to evaluate the efficacy and safety of MK-8189 at a range of doses (8 mg, 16 mg, and 24 mg once daily) in adult participants who have an acute episode of schizophrenia according to Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) …

risperidone
Chiba University Hospital ( Site 2024)
 (9.6 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +49 other locations
Safety Tolerability and Efficacy of Zilucoplan in Subjects With Generalized Myasthenia Gravis

The RAISE study is a multicenter, randomized, double-blind, placebo controlled study to confirm the efficacy, safety, and tolerability of zilucoplan in subjects with generalized Myasthenia Gravis. Subjects will be randomized in a 1:1 ratio to receive daily SC doses of 0.3 mg/kg zilucoplan or placebo for 12 weeks.

corticosteroids
ra101495
serologic test
immunosuppressive agents
generalized myasthenia gravis
International University of Health and Welfare Narita Hospital
 (4.7 away) Contact site
  • 97 views
  • 13 Jun, 2021
  • +148 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
mini-mental state examination
alzheimer's disease
positron emission tomography
flortaucipir
Inage Neurology and Memory Clinic
 (9.2 away) Contact site
  • 79 views
  • 13 Jun, 2021
  • +382 other locations
TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

A 3-Year Multi-Center, Long-Term Safety (LTS) Study to Evaluate the Safety and Tolerability of TD-1473 in Subjects with Ulcerative Colitis who have participated in the Maintenance Study of Protocol 0157

remission
Theravance Biopharma Investigational Site
 (10.0 away) Contact site
  • 7 views
  • 28 Jan, 2021
  • +158 other locations
Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

The purpose of this study is to evaluate the efficacy and safety of lenvatinib and pembrolizumab in combination with TACE versus TACE plus oral and intravenous (IV) placebos in participants with incurable, non-metastatic hepatocellular carcinoma (HCC). The primary hypotheses are that pembrolizumab plus lenvatinib in combination with TACE is superior …

chemoembolization
metastatic hepatocellular carcinoma
lenvatinib
hepatitis
TACE
Chiba University Hospital ( Site 0346)
 (9.6 away) Contact site
  • 79 views
  • 15 Jun, 2021
  • +165 other locations
Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

fibrosis
hepatic fibrosis
steatohepatitis
Chiba University Hospital
 (9.6 away) Contact site
  • 72 views
  • 10 Jun, 2021
  • +317 other locations
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)

The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.

Chiba Cancer Center
 (9.9 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +134 other locations
Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice Daily Over 12 Weeks Work in Comparison to an Inactive Pill (Placebo) and Elagolix in Women Suffering From Pain Related to a Condition Where the Tissue That Usually Grows Inside the Womb Grows Outside of the Womb

The purpose of this study is to assess safety and efficacy of BAY1817080 compared to elagolix and placebo in women with symptomatic endometriosis. Study details include: Study duration: 155 up to 285 days Treatment duration: 84 days Visit frequency: approximately once a month

laparoscopy
laparotomy
ibuprofen
analgesic
elagolix
Aiiku Ladies Clinic
 (9.1 away) Contact site
  • 0 views
  • 03 Jun, 2021
  • +201 other locations
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on cognitive decline using the Alzheimer's Disease Assessment Scale Cognitive subscale 13-item version (ADAS-Cog13).

cognitive decline
cognitive assessment
alzheimer's disease
dementia
Inage Neurology and Memory Clinic
 (9.2 away) Contact site
  • 0 views
  • 03 Jun, 2021
  • +141 other locations