Ota, Japan Clinical Trials

A listing of Ota, Japan clinical trials actively recruiting patients volunteers.

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Found 580 clinical trials
Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung04)

This study will assess safety, tolerability, and treatment activity of datopotamab deruxtecan (Dato-DXd) in combination with durvalumab in participants with advanced or metastatic non-small cell lung cancer (NSCLC).

The Cancer Institute Hospital of Japanese Foundation For Cancer Research
 (6.7 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +20 other locations
Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF

The primary objective of the trial is the confirmation of the efficacy of apraglutide to evaluate the efficacy of weekly subcutaneous apraglutide in reducing parenteral support dependency.

Yokohama Municipal Citizen's Hospital
 (7.8 away) Contact site
  • 0 views
  • 11 Jul, 2021
  • +45 other locations
Study of Ravulizumab in Pediatric Participants With HSCT-TMA

This study will evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of ravulizumab administered by intravenous infusion to pediatric participants, from 1 month to < 18 years of age, with HSCT-TMA. The treatment period is 26 weeks, followed by a 26-week off-treatment follow-up period.

Clinical Trial Site
 (6.8 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +33 other locations
A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

This study aims to define the efficacy and safety of inebilizumab for the prevention of flare of IgG4-related disease (IgG4-RD).

Viela Bio Investigative Site
 (8.7 away) Contact site
  • 0 views
  • 20 Jun, 2021
  • +85 other locations
Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplastic Anemia

This study is designed to evaluate the efficacy and safety of eltrombopag when added to r-ATG and CsA in treatment naive East-Asian adult and pediatric patients with SAA.

Novartis Investigative Site
 (8.1 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +12 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

macitentan
right heart catheterization
macitentan 10 mg
hypertension
connective tissue disease
Toho University Medical Center Omori Hospital
 (0.7 away) Contact site
  • 56 views
  • 16 Jul, 2021
  • +265 other locations
Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

This is a Phase 3 open-label, multicenter, randomized, active-controlled study designed to compare the efficacy and safety and tolerability of P1101 compared with ANA after 12 months of treatment as second-line therapy for subjects with ET who have had a suboptimal or failed response to HU.

ropeginterferon alfa-2b
interferon
hydroxyurea
neutrophil count
anagrelide
NTT Medical Center Tokyo
 (4.6 away) Contact site
  • 0 views
  • 20 Mar, 2021
  • +50 other locations
A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer

This study is designed to primarily evaluate the safety and efficacy of U3-1402 in participants with advanced or metastatic colorectal cancer (CRC) who have received at least 2 prior lines of therapy and will explore clinical benefit according to human epidermal growth factor receptor 3 (HER3) tumor expression level in …

fluoropyrimidine
measurable disease
microsatellite instability high
neutrophil count
oxaliplatin
The Cancer Institute Hospital of JFCR
 (6.7 away) Contact site
  • 0 views
  • 13 Feb, 2021
  • +42 other locations
Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)

This study will assess safety and treatment activity of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab with or without platinum chemotherapy in participants with advanced or metastatic non-small cell lung cancer.

Showa Univeristy Hospital
 (3.4 away) Contact site
  • 14 views
  • 21 Jul, 2021
  • +22 other locations
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine

The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days …

Tokyo Headache Clinic
 (8.1 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +78 other locations